The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation.

The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation. Abstract Text:

Juliana Leal,Fabio M Squina,Nilce M Martinez-Rossi,Antonio Rossi,Juliana Leal,Fabio M Squina,Nilce M Martinez-Rossi,Antonio Rossi,

The preg gene encodes a cyclin-like protein that is implicated in the derepression of nucleases and phosphatases that scavenge phosphate from the environment. To better understand the regulatory role of the preg gene product, the differential display reverse transcriptase - polymerase chain reaction was used to isolate transcripts differentially expressed in the pregc mutant strain of the mold Neurospora crassa grown under phosphate starvation, at pH 7.8. Two transcripts, whose differential expressions were confirmed by Northern blotting, were downregulated in a strain of N. crassa carrying a loss-of-function mutation in the preg gene (preg(c) allele). These transcripts revealed genes coding for enzymes involved in the thymidine salvage pathway (iso-orotate decarboxylase) and in the biosynthesis of coenzyme Q (ubiquinone C-methyltransferase), which may be relevant to a further understanding of the molecular events involved in the phosphorus sensing in N. crassa.

The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation. Publishing Authors By Initials

J Leal,FM Squina,NM Martinez-Rossi,A Rossi,J Leal,FM Squina,NM Martinez-Rossi,A Rossi,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Canadian journal of microbiology

VOLUME: 53

Page Numbers: 1011-5

Journal Abbreviation: Can. J. Microbiol.

ISSN: 0008-4166

DAY: 27

MONTH: Aug

YEAR: 2007

The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 372707

The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation.

AFFILIATION: Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Av Bandeirantes 3900, 14049-900, Ribeirão Preto, SP, Brazil.

Country: Canada

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Can J Microbiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The transcription of the gene for iso-orotate decarboxylase IDCase, an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation Related Publications

• 4,5-Dihydro-11-NOR-11-Hydroxy-Delta 7,11-Santonin, A New NOR-Sesquiterpene-gamma-Lactone Found in Crepis pygmaea.
• A facile lentiviral vector system for expression of doxycycline-inducible shRNAs: knockdown of the pre-miRNA processing enzyme Drosha.
• Acute, but not chronic, leptin treatment induces acyl-CoA oxidase in C2C12 myotubes.
• Alcoholism: effects on the cochleo-vestibular apparatus.
• Association between dynamic asymmetry of the newborn's head and intrauterine factors.
• Cloning and Detecting Signature MicroRNAs from Mammalian Cells.
• Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC.
• Design of a stage-matched intervention trial to increase dual method contraceptive use (Project PROTECT).
• Distance constraints between microRNA target sites dictate efficacy and cooperativity.
• Evaluation of the reproductive efficiency of simmental and Friesian dairy cows farmed in Friuli (Northeast Italy) by the analysis of progesterone levels.
• Experimental study comparing the tensile strength of different surgical meshes following aponeurotic-muscle deformity synthesis on Wistar rats.
• Exploration of irony appreciation in schizophrenia: a replication study on an Italian sample.
• Flavonoids from Dittrichia viscosa.
• Generation of distinct types of periglomerular olfactory bulb interneurons during development and in adult mice: implication for intrinsic properties of the subventricular zone progenitor population.
• Human leukocyte antigen and adult living-donor liver transplantation outcomes: an analysis of the organ procurement and transplantation network database.
• Improvement of dissolution rate of piroxicam by inclusion into MCM-41 mesoporous silicate.
• Occipital pseudoaneurysm as a complication of extension channel placement for DBS in Parkinson's disease.
• Plasma membrane calcium pump activity is affected by the membrane protein concentration: evidence for the involvement of the actin cytoskeleton.
• Prophylactic treatment of haemophilia patients with inhibitors: clinical experience with recombinant factor VIIa in European Haemophilia Centres.
• Proton pump inhibitors in acute treatment of reflux oesophagitis : a cost-effectiveness analysis.
• RNAi therapeutics: principles, prospects and challenges.
• Rational design and in vitro and in vivo delivery of Dicer substrate siRNA.
• Reduced Peak Inspiratory Effort through the Diskus((R)) and the Turbuhaler((R)) due to Mishandling is Common in Clinical Practice.
• Studying the Cu binding sites in the PrP N-terminal region: a test case for ab initio simulations.
• Targeted cleavage: tuneable cis-cleaving ribozymes.
• The prognostic value of circulating tumor cells in patients with melanoma: a systematic review and meta-analysis.
• The transcription of the gene for iso-orotate decarboxylase (IDCase), an enzyme of the thymidine salvage pathway, is downregulated in the pregc mutant strain of Neurospora crassa grown under phosphate starvation.
• Use of calcined Mg-Al-hydrotalcite to enhance the stability of celecoxib in the amorphous form.
• [Clinical report. Soledad: from expression to communication.]
• [The combination of sugars with biomolecules. From the kitchen to the organism]