The Tip Growth Apparatus of Aspergillus nidulans.

The Tip Growth Apparatus of Aspergillus nidulans. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The Tip Growth Apparatus of Aspergillus nidulans. Abstract Text:

Hyphal tip growth in fungi is important because of the economic and medical importance of fungi, and because it may be a useful model for polarized growth in other organisms. We have investigated the central questions of the roles of cytoskeletal elements and of the precise sites of exocytosis and endocytosis at the growing hyphal tip by using the model fungus Aspergillus nidulans. Time-lapse imaging of fluorescent fusion proteins reveals a remarkably dynamic, but highly structured, tip growth apparatus. Live imaging of SYNA, a synaptobrevin homologue, and SECC, an exocyst component, reveals that vesicles accumulate in the Spitzenkörper (apical body) and fuse with the plasma membrane at the extreme apex of the hypha. SYNA is recycled from the plasma membrane by endocytosis at a collar of endocytic patches, 1-2 mum behind the apex of the hypha, that moves forward as the tip grows. Exocytosis and endocytosis are thus spatially coupled. Inhibitor studies, in combination with observations of fluorescent fusion proteins, reveal that actin functions in exocytosis and endocytosis at the tip and in holding the tip growth apparatus together. Microtubules are important for delivering vesicles to the tip area and for holding the tip growth apparatus in position.

The Tip Growth Apparatus of Aspergillus nidulans. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

The Tip Growth Apparatus of Aspergillus nidulans. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Molecular biology of the cell

VOLUME: 19

Page Numbers: 1439-49

Journal Abbreviation: Mol. Biol. Cell

ISSN: 1059-1524

DAY: 23

MONTH: 01

YEAR: 2008

The Tip Growth Apparatus of Aspergillus nidulans. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9201390

The Tip Growth Apparatus of Aspergillus nidulans. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The Tip Growth Apparatus of Aspergillus nidulans. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The Tip Growth Apparatus of Aspergillus nidulans.

AFFILIATION: *Department of Molecular Genetics, The Ohio State University, Columbus, OH 43210; Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima 770-8503, Japan.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Mol Biol Cell

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The Tip Growth Apparatus of Aspergillus nidulans Related Publications

• Aromatic 4-tetrahydropyranyl and 4-quinuclidinyl cations. Linking Prins with Cope and Grob.
• Cardiovascular disease in pregnancy.
• Chlorpropamide in the treatment of diabetes mellitus.
• Comparative tests of evolutionary trade-offs in a palinurid lobster acoustic system.
• Culturally competent training program: a key to training lay health advisors for promoting breast cancer screening.
• Cyril Leslie Oakley, 20 June 1907--27 March 1975.
• Erratic rates of molecular evolution and incongruence of fossil and molecular divergence time estimates in Ostracoda (Crustacea).
• Ferromagnetism in a heavy atom heterocyclic radical conductor.
• Fifty years of JN Morris's Uses of Epidemiology.
• Fusion PCR and gene targeting in Aspergillus nidulans.
• Glucose tolerance and serum insulin in the unaffected first-degree relatives of diabeteics.
• Glucose tolerance and serum insulin in the unaffected first-degree relatives of diabetics.
• Heart disease in pregnancy.
• Infective endocarditis in three patients with hypertrophic obstructive cardiomyopathy.
• Major trauma & cervical clearance radiation doses & cancer induction.
• NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse.
• NF-kappaB is a critical regulator of the survival of rodent and human hepatic myofibroblasts.
• Nuclear factor-kappaB1: Regulation and function.
• Reconstructing ancestral genome content based on symmetrical best alignments and Dollo parsimony.
• Single- and double-contrast techniques in esophagitis.
• Spin-canting in heavy atom heterocyclic radicals.
• The Origins of Novel Protein Interactions during Animal Opsin Evolution.
• The Tip Growth Apparatus of Aspergillus nidulans.
• The hypertrophic cardiomyopathies.
• The new biology: beyond the Modern Synthesis.
• The prevalence of a diabetic condition and adhesive capsulitis of the shoulder.
• Today's multiple choice exam: (a) gene duplication; (b) structural mutation; (c) co-option; (d) regulatory mutation; (e) all of the above.
• Type II Opsins: Evolutionary Origin by Internal Domain Duplication?
• Upright static pelvic posture as rotations and translations in 3-dimensional from three 2-dimensional digital images: validation of a computerized analysis.
• Use of optical dilating trocar for initial access during extraperitoneal laparoscopic radical prostatectomy.