The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ.

The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ. Abstract Text:

Rae Silver,William J Schwartz,

Ever since the locus of the brain clock in the suprachiasmatic nucleus (SCN) was first described, methods available have both enabled and encumbered our understanding of its nature at the level of the cell, the tissue, and the animal. A combination of in vitro and in vivo approaches has shown that the SCN is a complex heterogeneous neuronal network. The nucleus is composed of cells that are retinorecipient and reset by photic input; those that are reset by nonphotic inputs; slave oscillators that are rhythmic only in the presence of the retinohypothalamic tract; endogenously rhythmic cells, with diverse period, phase, and amplitude responses; and cells that do not oscillate, at least on some measures. Network aspects of SCN organization are currently being revealed, but mapping these properties onto cellular characteristics of electrical responses and patterns of gene expression are in early stages. While previous mathematical models focused on properties of uniform coupled oscillators, newer models of the SCN as a brain clock now incorporate oscillator and gated, nonoscillator elements.

The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ. Publishing Authors By Initials

R Silver,WJ Schwartz,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Methods in enzymology

VOLUME: 393

Page Numbers: 451-65

Journal Abbreviation: Meth. Enzymol.

ISSN: 0076-6879

DAY: 8

MONTH: 04

YEAR: 2005

The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 212271

The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ.

AFFILIATION:

Country: United States

AGENCY: United States NINDS

GRANT: R01 NS046605-02

ACRONYM: NS

MEDLINETA: Methods Enzymol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ Related Publications

• A dominant-negative p65 PAK peptide inhibits angiogenesis.
• After the war on terrorism, an attack on antibiotic resistance.
• Antiphase oscillation of the left and right suprachiasmatic nuclei.
• Changes in systolic blood pressure associated with lead in blood and bone.
• EDITORIAL: Globalization of Pediatrics.
• EDITORIAL:: Preparing for Future Amazement.
• Editorial.
• Editorial.
• Evaluation of 2 novel approaches for assessing the ability of demineralized freeze-dried bone allograft to induce new bone formation.
• Evidence for a coupling of synthesis and export of an outer membrane protein in Escherichia coli.
• Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2.
• In vivo DTI evaluation of white matter tracts in rat spinal cord.
• Integrative capacity of the caudal brainstem in the control of food intake.
• Lipid-lowering pharmacoeconomic studies. Reactor panel and open forum.
• MR Imaging and Epilepsy-3T or not 3T? That Is the Question.
• Monoclonal antibodies reveal lamB antigenic determinants on both faces of the Escherichia coli outer membrane.
• Monoclonal antibody as a probe for structure and function of an Escherichia coli outer membrane protein.
• Mutations that alter the transport function of the LamB protein in Escherichia coli.
• Nonadiabatic molecular dynamics simulations of correlated electrons in solution. 1. Full configuration interaction (CI) excited-state relaxation dynamics of hydrated dielectrons.
• Occupational health in Brazil.
• Phage lambda receptor (lamB protein) in Escherichia coli.
• Potential of porous poly-D,L-lactide-co-glycolide particles as a carrier for recombinant human bone morphogenetic protein-2 during osteoinduction in vivo.
• Recombinant bone morphogenetic protein (BMP)-2 regulates costochondral growth plate chondrocytes and induces expression of BMP-2 and BMP-4 in a cell maturation-dependent manner.
• Reconsidering the early steps of protein secretion.
• Taxotere-induced inhibition of human endothelial cell migration is a result of heat shock protein 90 degradation.
• The ISPOR Lipid Conference: Pharmacoeconomics and Outcomes Modeling Issues.
• The Suprachiasmatic Nucleus is a Functionally Heterogeneous Timekeeping Organ.
• Transition path sampling study of classical rate-promoting vibrations.
• Using Per gene expression to search for photoperiodic oscillators in the hamster suprachiasmatic nucleus.
• p21-activated kinase regulates endothelial permeability through modulation of contractility.