The study on cell surface antigens in epithelial tumor of the upper urinary tract: ABH-isoantigen and Thomsen-Friedenreich antigen.

The study on cell surface antigens in epithelial tumor of the upper urinary tract: ABH-isoantigen and Thomsen-Friedenreich antigen. Research Abstract Details 

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The study on cell surface antigens in epithelial tumor of the upper urinary tract: ABH-isoantigen and Thomsen-Friedenreich antigen. Abstract Text:

H Fukatsu,H Nonomura,Y Miyagawa,M Waki,Y Hatano,S Hiraiwa,T Muramatsu,E Nishikawa,Y Yamada,T Satoh,

ABH-isoantigen (ABH-Ag) and Thomsen-Friedenreich antigen (T-Ag) were investigated by the Avidin-Biotin-Peroxidase Complex (ABC) method on 47 patients with epithelial tumor of the upper urinary tract (all patients underwent nephroureterectomy including the cuff of the bladder; 30 patients were diagnosed as transitional cell carcinoma of renal pelvis and 17 ureteral organs). The correlations between ABC expression for ABH-Ag and T-Ag with histological grade, stage and prognosis (5 year survival rate) were studied. A correlation was observed between grade (p less than 0.05) and deletion of the antigenicity of ABH-Ag, but no correlation was evident with stage and prognosis. A high correlation was evident, however, between grade (p less than 0.01), stage (p less than 0.01) and prognosis (p less than 0.01) and deletion of the antigenicity of T-Ag. The analysis of ABC expression for ABH-Ag and T-Ag may therefore be valuable for predicting the malignant potential in transitional cell carcinoma of the upper urinary tract. T-Ag determination in particular may provide a useful prognostic probe should it find clinical application.

The study on cell surface antigens in epithelial tumor of the upper urinary tract: ABH-isoantigen and Thomsen-Friedenreich antigen. Publishing Authors By Initials

H Fukatsu,H Nonomura,Y Miyagawa,M Waki,Y Hatano,S Hiraiwa,T Muramatsu,E Nishikawa,Y Yamada,T Satoh,

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The study on cell surface antigens in epithelial tumor of the upper urinary tract: ABH-isoantigen and Thomsen-Friedenreich antigen. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Hinyokika kiyo. Acta urologica Japonica

VOLUME: 35

Page Numbers: 949-54

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ISSN: 0018-1994

DAY: 5

MONTH: Jun

YEAR: 1989

The study on cell surface antigens in epithelial tumor of the upper urinary tract: ABH-isoantigen and Thomsen-Friedenreich antigen. Information

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LANGUAGE: eng

NlmUniqueID: 421145

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Grant and Affiliation Information for The study on cell surface antigens in epithelial tumor of the upper urinary tract: ABH-isoantigen and Thomsen-Friedenreich antigen.

AFFILIATION: Department of Urology, Aichi Medical University.

Country: JAPAN

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MEDLINETA: Hinyokika Kiyo

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