The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation.

The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation. Research Abstract Details 

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The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation. Abstract Text:

Y Banno,H P Morris,N Katunuma,

1. Hepatoma 8999 showed extremely high activity of serine protease, but similar activities of other lysosomal proteases to those of normal rat liver. 2. Serine protease from rat liver formed a single immunoprecipitation band against antiserum to purified protease from hepatoma 8999. 3. The serine proteases in rat liver and hepatoma 8999 were restricted to the inner membranes of the mitochondrial fraction. 4. Polyacrylamide gel electrophoresis with sodium dodecylsulfate showed that hepatoma 8999 mitochondria contained less of the slowest moving protein component than rat liver mitochondrial protein. This component was found to be the best substrate for mitochondrial serine protease in both liver and hepatoma 8999. 5. The role of serine protease in mitochondrial protein degradation is discussed on the basis of these results.

The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation. Publishing Authors By Initials

Y Banno,HP Morris,N Katunuma,

For similar amino acids, peptides, and proteins: amino acids: amino acids, neutral: serine research abstracts see: amino acids, peptides, and proteins: amino acids: amino acids, neutral: serine research

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The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 83

Page Numbers: 1545-54

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jun

YEAR: 1978

The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation. Information

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LANGUAGE: eng

NlmUniqueID: 376600

The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation. Keywords Mesh Terms:

KEYWORDS: Serine

MESH TERMS: metabolism

Chemical & Substance for Abstract: The serine protease from rat liver and hepatoma 8999. Location and role in mitochondrial protein degradation. Information

Substance Name: Peptide Hydrolases

Registry Number: EC 3.4.-

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Country: JAPAN

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MEDLINETA: J Biochem

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