The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis.

The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis. Research Abstract Details 

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The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis. Abstract Text:

Heather Maughan,Joanna Masel,C William Birky,Wayne L Nicholson,

Phenotypic loss is an important evolutionary force in nature but the mechanism(s) responsible for loss remains unclear. We used both simulation and multiple-regression approaches to analyze data on the loss of sporulation, a complex bacterial developmental process, during experimental evolution of Bacillus subtilis. Neutral processes of mutational degradation alone were sufficient to explain loss-of-sporulation ability in four of five populations, while evidence that selection facilitated mutational loss was found for only one population. These results are discussed in the context of the evolution of sporulation in particular and phenotypic loss in general.

The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis. Publishing Authors By Initials

H Maughan,J Masel,CW Birky,WL Nicholson,

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The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Genetics

VOLUME: 177

Page Numbers: 937-48

Journal Abbreviation: Genetics

ISSN: 0016-6731

DAY: 24

MONTH: 08

YEAR: 2007

The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis. Information

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LANGUAGE: eng

NlmUniqueID: 374636

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Grant and Affiliation Information for The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis.

AFFILIATION: Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA. maughan@zoology.ubc.ca

Country: United States

AGENCY: United States NIGMS

GRANT: GM-076041

ACRONYM: GM

MEDLINETA: Genetics

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