[The role of fatty acids in gene regulation. An example of an important nutritional factor which may influence our genes]

[The role of fatty acids in gene regulation. An example of an important nutritional factor which may influence our genes] Research Abstract Details 

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[The role of fatty acids in gene regulation. An example of an important nutritional factor which may influence our genes] Abstract Text:

Regulation of gene expression by specific nutrients has become a major field of nutrition research. Evidence is presented showing that dietary constituents specifically modulate gene transcription and transcript processing. The peroxisome proliferator-activated receptor (PPAR) is a member of the steroid hormone receptor superfamily and is activated by a variety of hypolipidemic drugs, termed peroxisome proliferators. Several genes have been shown to contain elements responsive to peroxisome proliferator-activated receptor. These include the genes that encode the peroxisomal enzymes involved in beta-oxidation of fatty acids. The retinoid receptor X is required, however, for PPAR to bind to its responsive element. The finding that fatty acids are PPAR activators suggests that fatty acids or their acyl CoA-derivatives may regulate the lipid metabolism via this receptor.

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[The role of fatty acids in gene regulation. An example of an important nutritional factor which may influence our genes] Journal Published:

PUBLICATION TYPE: Review

Journal: Tidsskrift for den Norske lægeforening : tidsskrif

VOLUME: 115

Page Numbers: 2084-6

Journal Abbreviation: Tidsskr. Nor. Laegeforen.

ISSN: 0029-2001

DAY: 30

MONTH: Jun

YEAR: 1995

[The role of fatty acids in gene regulation. An example of an important nutritional factor which may influence our genes] Information

Number of References: 17

LANGUAGE: nor

NlmUniqueID: 413423

[The role of fatty acids in gene regulation. An example of an important nutritional factor which may influence our genes] Keywords Mesh Terms:

KEYWORDS: Transcription Factors

MESH TERMS: physiology

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Substance Name: Transcription Factors

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Grant and Affiliation Information for [The role of fatty acids in gene regulation. An example of an important nutritional factor which may influence our genes]

AFFILIATION: Ernaeringsinstituttet, Blindern, Oslo.

Country: NORWAY

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MEDLINETA: Tidsskr Nor Laegeforen

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