Three classes of antifungals--polyenes, extended-spectrum azoles, and echinocandins--are now available for treating systemic fungal infections. Guidance for the appropriate use of this expanded variety of antifungals may come from recent clinical trials. Extended-spectrum azoles have excellent in vitro activity against Aspergillus and have been shown to improve clinical outcomes. For Zygomycetes, along with the lipid formulations of amphotericin, of the new agents, only posaconazole has activity. For Candida, the echinocandins offer a broad spectrum of activity. These new agents offer less toxicity and potentially improved efficacy in these difficult infections.
The Role of Echinocandins, Extended-spectrum Azoles, and Polyenes to Treat Opportunistic Moulds and Candida. Publishing Authors By Initials
The Role of Echinocandins, Extended-spectrum Azoles, and Polyenes to Treat Opportunistic Moulds and Candida. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Current infectious disease reports
VOLUME: 8
Page Numbers: 442-8
Journal Abbreviation:
ISSN: 1523-3847
DAY: 26
MONTH: Nov
YEAR: 2006
The Role of Echinocandins, Extended-spectrum Azoles, and Polyenes to Treat Opportunistic Moulds and Candida. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 100888983
The Role of Echinocandins, Extended-spectrum Azoles, and Polyenes to Treat Opportunistic Moulds and Candida. Keywords Mesh Terms:
KEYWORDS:
MESH TERMS:
Chemical & Substance for Abstract: The Role of Echinocandins, Extended-spectrum Azoles, and Polyenes to Treat Opportunistic Moulds and Candida. Information
Substance Name:
Registry Number:
Grant and Affiliation Information for The Role of Echinocandins, Extended-spectrum Azoles, and Polyenes to Treat Opportunistic Moulds and Candida.
AFFILIATION: The University of Texas Health Science Center at San Antonio, Department of Medicine/Infectious Diseases, 7703 Floyd Curl Drive, Mail Code 7881, San Antonio, TX 78229-3900, USA. patterson@uthscsa.edu.
Country: United States
AGENCY:
GRANT:
ACRONYM:
MEDLINETA: Curr Infect Dis Rep
REFSOURCE:
DATABASENAME:
ACCESSION NUMBER:
Number Hits: 0
The Role of Echinocandins, Extended-spectrum Azoles, and Polyenes to Treat Opportunistic Moulds and Candida Related Publications