The relationship between brain morphometry and neuropsychological performance in alcohol dependence.

The relationship between brain morphometry and neuropsychological performance in alcohol dependence. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The relationship between brain morphometry and neuropsychological performance in alcohol dependence. Abstract Text:

Dong-Pyo Jang,Kee Namkoong,Jae-Jin Kim,Sangjin Park,In-Young Kim,Sun I Kim,Young-Bo Kim,Zang-Hee Cho,Eun Lee,Dong-Pyo Jang,Kee Namkoong,Jae-Jin Kim,Sangjin Park,In-Young Kim,Sun I Kim,Young-Bo Kim,Zang-Hee Cho,Eun Lee,

The aim of this study was to explore local brain atrophy of patients with alcohol dependence using a voxel-based analysis of magnetic resonance images and to investigate the relationship of those atrophic regions with drinking history and neuropsychological performances. Statistical parametric mapping was applied for the global and regional comparison of segmented gray matter and white matter images from 20 patients with alcohol dependence and with those from 20 controls. The Rey auditory-verbal learning test, Rey-Osterrieth complex figure test, Stroop test, trail-making test, and Wisconsin card sorting test were conducted as neuropsychological evaluations. There was a significant decrease in both gray matter and white matter globally in alcohol dependence. Bilateral parahippocampal white matter areas were reduced in particular. Perseverative responses and perseverative errors in the Wisconsin card sorting test had significant correlation with the decrease of gray matter decrease including the left superior temporal gyri and right postcentral region. The psychological performance measures correlated with gray matter rather than white matter, whereas right temporal white matter correlated with drinking amount for last 4 weeks. This may imply that alcohol consumption in heavy amounts damages both gray matter and white matter, and gray matter atrophy mainly leads to cognitive impairment, whereas white matter is related to drinking history.

The relationship between brain morphometry and neuropsychological performance in alcohol dependence. Publishing Authors By Initials

DP Jang,K Namkoong,JJ Kim,S Park,IY Kim,SI Kim,YB Kim,ZH Cho,E Lee,DP Jang,K Namkoong,JJ Kim,S Park,IY Kim,SI Kim,YB Kim,ZH Cho,E Lee,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

The relationship between brain morphometry and neuropsychological performance in alcohol dependence. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Neuroscience letters

VOLUME: 428

Page Numbers: 21-6

Journal Abbreviation: Neurosci. Lett.

ISSN: 0304-3940

DAY: 29

MONTH: 09

YEAR: 2007

The relationship between brain morphometry and neuropsychological performance in alcohol dependence. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7600130

The relationship between brain morphometry and neuropsychological performance in alcohol dependence. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The relationship between brain morphometry and neuropsychological performance in alcohol dependence. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The relationship between brain morphometry and neuropsychological performance in alcohol dependence.

AFFILIATION: Neuroscience Research Institute, Gachon University of Medicine and Science, Incheon, Korea.

Country: Ireland

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Neurosci Lett

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The relationship between brain morphometry and neuropsychological performance in alcohol dependence Related Publications

• A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light.
• Actual Conditions and Countermeasure of Yun-bian Old Men's Health.
• Aspirin changes the secretion rate and amino acid composition of human small intestinal mucin in subjects with ileal conduits.
• Bone morphogenetic protein-2 facilitates expression of chondrogenic, not osteogenic, phenotype of human intervertebral disc cells.
• Channel architecture in maltoporin: dominance studies with lamB mutations influencing maltodextrin binding provide evidence for independent selectivity filters in each subunit.
• Compensation. Costly to a fault.
• Design and feasibility of quick EXAFS scans for a 'broomstick' double-crystal monochromator at PLS beamline.
• Directed evolution of the lambda receptor of Escherichia coli through affinity chromatographic selection.
• Effects of dietary vitamin E supplementation on lipid oxidation and volatiles content of irradiated, cooked turkey meat patties with different packaging.
• Exclusion of high-molecular-weight maltosaccharides by lipopolysaccharide O-antigen of Escherichia coli and Salmonella typhimurium.
• Family decision making for elderly patients in the intensive care unit.
• Identification of an osteogenic protein-1 responsive element in the aggrecan promoter.
• Impairment of conjunctival glutathione secretion and ion transport by oxidative stress in an adenovirus type 5 ocular infection model of pigmented rabbits.
• Inactivation of the PTEN gene protein product is associated with the invasiveness and metastasis, but not angiogenesis, of breast cancer.
• Isolation, by affinity chromatography, of mutant escherichia coli cells with novel regulation of lamB expression.
• Longitudinal clivus fracture associated with trapped basilar artery: unusual survival with good neurological recovery.
• MPer1 and mper2 are essential for normal resetting of the circadian clock.
• Model construction on quality of family caregiving in the elderly.
• Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.
• Photoionization studies of sulfur radicals and products of their reactions.
• Posterior transarticular screw fixation for chronic atlanto-axial instability.
• Reciprocal regulation of haem biosynthesis and the circadian clock in mammals.
• Restoration of a loose implant supported crown: a case report.
• Significance of chronic epilepsy in glial tumors and correlation with surgical strategies.
• The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo.
• The effects of permeation enhancers on the surface morphology of the rat nasal mucosa: a scanning electron microscopy study.
• The influence of maltoporin affinity on the transport of maltose and maltohexaose into Escherichia coli.
• Tissue-specific expression, heat inducibility, and biological roles of two hsp16 genes in Caenorhabditis elegans.
• Up-regulation of MUC5AC and MUC5B mucin genes in chronic rhinosinusitis.
• [Expression of MUC3, MUC5AC, MUC6 and epidermal growth factor receptor in gallbladder epithelium according to gallstone composition]