The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers.

The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers. Research Abstract Details 

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The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers. Abstract Text:

Jobst Henker,Martin Laass,Boris M Blokhin,Yuriy K Bolbot,Vitaliy G Maydannik,Martina Elze,Corinna Wolff, Schulze,

In most cases, acute diarrhoea will become self-limiting during the first few days after onset. For young children, however, health risks may develop when the disease lasts longer than 3 days. The purpose of the present trial was to determine whether the stool frequency of infants and toddlers suffering from acute diarrhoea could be normalised more quickly by administering the probiotic Escherichia coli Nissle 1917 (EcN) solution than by administering a placebo. The safety of EcN were also assessed. A total of 113 children (aged 2-47 months) with acute diarrhoea (> three watery or loose stools in 24 h) were randomised to either a group receiving the probiotic EcN suspension (n = 55) or a group receiving the placebo suspension (n = 58) in a confirmative, double-blind clinical trial. Depending on the age of patients, 1-3 ml per day of verum suspension (10(8) viable EcN cells per millilitre) or placebo were administered orally. The causes of the diarrhoea were viral rather than bacterial, but they were mainly unspecific infections. The median onset of treatment response (reduction of daily stool frequency to

The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers. Publishing Authors By Initials

J Henker,M Laass,BM Blokhin,YK Bolbot,VG Maydannik,M Elze,C Wolff,J Schulze,

For similar diagnosis: prognosis: treatment outcome research abstracts see: diagnosis: prognosis: treatment outcome research

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The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: European journal of pediatrics

VOLUME: 166

Page Numbers: 311-8

Journal Abbreviation: Eur. J. Pediatr.

ISSN: 0340-6199

DAY: 8

MONTH: 02

YEAR: 2007

The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers. Information

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LANGUAGE: eng

NlmUniqueID: 7603873

The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers. Keywords Mesh Terms:

KEYWORDS: Treatment Outcome

MESH TERMS: administration & dosage

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Substance Name: Suspensions

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Grant and Affiliation Information for The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers.

AFFILIATION: Department of Paediatrics, University Hospital Carl-Gustav-Carus, Fetscherstrasse 74, 01307, Dresden, Germany. Jobst.Henker@uniklinikum-dresden.de

Country: Germany

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MEDLINETA: Eur J Pediatr

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