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The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States.

The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Research Abstract Details 

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  • The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Abstract Text:

    michael d kappelmanMichael D Kappelman,sheryl l rifas-shimanSheryl L Rifas-Shiman,ken kleinmanKen Kleinman,dan ollendorfDan Ollendorf,athos bousvarosAthos Bousvaros,richard j grandRichard J Grand,jonathan a finkelsteinJonathan A Finkelstein,michael d kappelmanMichael D Kappelman,sheryl l rifas-shimanSheryl L Rifas-Shiman,ken kleinmanKen Kleinman,dan ollendorfDan Ollendorf,athos bousvarosAthos Bousvaros,richard j grandRichard J Grand,jonathan a finkelsteinJonathan A Finkelstein,

    BACKGROUND & AIMS: Previous US studies of inflammatory bowel disease (IBD) prevalence have sampled small, geographically restricted populations and may not be generalizable to the entire nation. This study sought to determine the prevalence of Crohn's disease (CD) and ulcerative colitis (UC) in a large national sample and to compare the prevalence across geographic regions and other sociodemographic characteristics. METHODS: We analyzed the health insurance claims for 9 million Americans, pooled from 87 health plans in 33 states, and identified cases of CD and UC using diagnosis codes. Prevalence was determined by dividing the number of cases by the number of persons enrolled for 2 years. Logistic regression was used to compare prevalence estimates by geographic region, age, sex, and insurance type (Medicaid vs commercial). RESULTS: The prevalence of CD and UC in children younger than 20 years was 43 (95% confidence interval [CI], 40-45) and 28 (95% CI, 26-30) per 100,000, respectively. In adults, the prevalence of CD and UC was 201 (95% CI, 197-204) and 238 (95% CI, 234-241), respectively. The prevalence of both conditions was lower in the South, compared with the Northeast, Midwest, and West. IBD appears to be more common in commercially insured individuals, compared with those insured by Medicaid. CONCLUSIONS: This estimation of the prevalence of IBD in the US should help quantify the overall burden of disease and inform the planning of appropriate clinical services.

    The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Publishing Authors By Initials

    md kappelmanMD Kappelman,sl rifas-shimanSL Rifas-Shiman,k kleinmanK Kleinman,d ollendorfD Ollendorf,a bousvarosA Bousvaros,rj grandRJ Grand,ja finkelsteinJA Finkelstein,md kappelmanMD Kappelman,sl rifas-shimanSL Rifas-Shiman,k kleinmanK Kleinman,d ollendorfD Ollendorf,a bousvarosA Bousvaros,rj grandRJ Grand,ja finkelsteinJA Finkelstein,

    For similar abstracts research abstracts see: abstracts research

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    The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Clinical gastroenterology and hepatology : the off

    VOLUME: 5

    Page Numbers: 1424-9

    Journal Abbreviation: Clin. Gastroenterol. Hepatol.

    ISSN: 1542-7714

    DAY: 29

    MONTH: 09

    YEAR: 2007

    The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Information

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    LANGUAGE: eng

    NlmUniqueID: 101160775

    The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Keywords Mesh Terms:

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    Grant and Affiliation Information for The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States.

    AFFILIATION: Center for Inflammatory Bowel Disease, Division of Gastroenterology and Nutrition, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA. michael_kappelman@med.unc.edu

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Clin Gastroenterol Hepatol

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