The potential anti-inflammatory benefits of improving physical fitness in hypertension.

The potential anti-inflammatory benefits of improving physical fitness in hypertension. Research Abstract Details 

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The potential anti-inflammatory benefits of improving physical fitness in hypertension. Abstract Text:

Kate M Edwards,Michael G Ziegler,Paul J Mills,

Hypertension is associated with an increased risk of stroke and atherosclerosis. In addition to elevated blood pressure, hypertension is characterized by neuroendocrine and immune activation, including elevated levels of C-reactive protein, inflammatory cytokines, and soluble adhesion molecules, which are predictive of morbidity and mortality outcomes. Pharmacological treatment for hypertension reduces blood pressure, but has limited effectiveness in reducing the accompanying inflammation and its associated morbidity and mortality. Exercise and diet interventions regularly show reductions in blood pressure in hypertensive individuals. Similar interventions in other populations show reductions in many inflammatory markers, but these effects have not been routinely examined in hypertensive individuals. The mechanisms through which exercise might exert an anti-inflammatory action include the sympathetic nervous system, the hypothalamic-pituitary-adrenal axis, as well as direct effects of blood pressure. Here, exercise is promoted as a potentially effective treatment for both the elevated blood pressure and chronic inflammation found in hypertension.

The potential anti-inflammatory benefits of improving physical fitness in hypertension. Publishing Authors By Initials

KM Edwards,MG Ziegler,PJ Mills,

For similar human activities: physical fitness research abstracts see: human activities: physical fitness research

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The potential anti-inflammatory benefits of improving physical fitness in hypertension. Journal Published:

PUBLICATION TYPE: Review

Journal: Journal of hypertension

VOLUME: 25

Page Numbers: 1533-42

Journal Abbreviation: J. Hypertens.

ISSN: 0263-6352

DAY: 3

MONTH: Aug

YEAR: 2007

The potential anti-inflammatory benefits of improving physical fitness in hypertension. Information

Number of References: 142

LANGUAGE: eng

NlmUniqueID: 8306882

The potential anti-inflammatory benefits of improving physical fitness in hypertension. Keywords Mesh Terms:

KEYWORDS: Physical Fitness

MESH TERMS: prevention & control

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Grant and Affiliation Information for The potential anti-inflammatory benefits of improving physical fitness in hypertension.

AFFILIATION: Department of Psychiatry, UCSD Medical Center, University of California, San Diego, La Jolla, California 92093-0804, USA. kmedwards@ucsd.edu

Country: England

AGENCY: United States NCRR

GRANT: M01RR-00827

ACRONYM: RR

MEDLINETA: J Hypertens

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