The potent antibacterial activity of Sitafloxacin against fluoroquinolone-resistant clinical isolates of Vibrio cholerae O1.

The potent antibacterial activity of Sitafloxacin against fluoroquinolone-resistant clinical isolates of Vibrio cholerae O1. Research Abstract Details 

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The potent antibacterial activity of Sitafloxacin against fluoroquinolone-resistant clinical isolates of Vibrio cholerae O1. Abstract Text:

Jun Okuda,Thandavarayan Ramamurthy,Shinji Yamasaki,Jun Okuda,Thandavarayan Ramamurthy,Shinji Yamasaki,

The in vitro antibacterial activity of sitafloxacin using clinical isolates of Vibrio cholerae O1 was compared to other fluoroquinolones: ciprofloxacin, ofloxacin, sparfloxacin and levofloxacin. Against fluoroquinolone-resistant O1 strains, sitafloxacin was 4- to 16-fold more effective than other fluoroquinolones at MIC(90*). Against fluoroquinolone-susceptible O1 strains, the MIC(90) of sitafloxacin was 2- to 4-fold lower than other fluoroquinolones. This suggests sitafloxacin can be used in the treatment of infections caused by V. cholerae O1 strains including the fluoroquinolone-resistant strains.

The potent antibacterial activity of Sitafloxacin against fluoroquinolone-resistant clinical isolates of Vibrio cholerae O1. Publishing Authors By Initials

J Okuda,T Ramamurthy,S Yamasaki,J Okuda,T Ramamurthy,S Yamasaki,

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The potent antibacterial activity of Sitafloxacin against fluoroquinolone-resistant clinical isolates of Vibrio cholerae O1. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Microbiology and immunology

VOLUME: 51

Page Numbers: 467-9

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ISSN: 0385-5600

DAY: 20

MONTH: 04

YEAR: 2007

The potent antibacterial activity of Sitafloxacin against fluoroquinolone-resistant clinical isolates of Vibrio cholerae O1. Information

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LANGUAGE: eng

NlmUniqueID: 7703966

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Grant and Affiliation Information for The potent antibacterial activity of Sitafloxacin against fluoroquinolone-resistant clinical isolates of Vibrio cholerae O1.

AFFILIATION: New Product Research Laboratories I, Daiichi Pharmaceutical Co Ltd, Tokyo, Japan. okudaj@hiroshima-u.ac.jp

Country: Japan

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MEDLINETA: Microbiol Immunol

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