Torsades de Pointes (TdP) is a life-threatening ventricular arrhythmia that can be associated with metabolic abnormalities, exposure to arrhythmogenic medications, and congenital long-QT syndrome. This report describes a patient with ALL and multiple complications of therapy who developed TdP. The patient had no evidence of congenital long-QT syndrome, but a constellation of factors appears to have led to QT prolongation, ventricular ectopy, and TdP. Although the patient suffered cardiac arrest, rapid recognition of TdP and prompt defibrillation resulted in an excellent outcome.
The perfect storm: Torsades de Pointes in a child with leukemia. Publishing Authors By Initials
The perfect storm: Torsades de Pointes in a child with leukemia. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Pediatric blood & cancer
VOLUME: 49
Page Numbers: 996-9
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ISSN: 1545-5009
DAY: 22
MONTH: Dec
YEAR: 2007
The perfect storm: Torsades de Pointes in a child with leukemia. Information
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LANGUAGE: eng
NlmUniqueID: 101186624
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Grant and Affiliation Information for The perfect storm: Torsades de Pointes in a child with leukemia.
AFFILIATION: Department of Pediatrics, Section of Pediatric Hematology/Oncology, University of Arizona Health Sciences Center, Tucson, Arizona 85724, USA. bagatell@peds.arizona.edu
Country: United States
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MEDLINETA: Pediatr Blood Cancer
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