The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba.

The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. Abstract Text:

Jan E Leuendorf,Andreas Genau,Agnieszka Szewczyk,Sutton Mooney,Christel Drewke,Eckhard Leistner,Hanjo Hellmann,

Vitamin B6 is one of the most important compounds in living organisms, and its biosynthesis has only recently been understood. Because it is required for more than 100 biochemical reactions, lack of the vitamin is fatal. This is of special importance to mammals and humans, which cannot biosynthesize the vitamin and thus depend on its external uptake. Here we describe the cloning of a vitamin B6 biosynthetic gene GbPDX1 from Ginkgo biloba. The gene is expressed in seeds, leaf and trunk tissue. Using yeast 2-hybrid and pull-down assays, we show that the protein can interact with itself and with members of Arabidopsis thaliana AtPDX1 and AtPDX2 families. Furthermore, we prove the function of GbPDX1 in vitamin B6 biosynthesis by complementation of an Arabidopsis AtPDX1.3 mutant rsr4-1, at the phenotypical level and increasing vitamin B6 levels caused by ectopic GbPDX1 expression in the mutant background. Overall, this study provides a first description of Ginkgo vitamin B6 metabolism, and demonstrates a high degree of conservation between Ginkgo and Arabidopsis.

The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. Publishing Authors By Initials

JE Leuendorf,A Genau,A Szewczyk,S Mooney,C Drewke,E Leistner,H Hellmann,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The FEBS journal

VOLUME: 275

Page Numbers: 960-9

Journal Abbreviation: FEBS J.

ISSN: 1742-464X

DAY: 26

MONTH: Mar

YEAR: 2008

The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101229646

The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba.

AFFILIATION: Angewandte Genetik, Freie Universität, Berlin, Germany.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: FEBS J

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba Related Publications

• An assessment of invasion risk from assisted migration.
• Bell-Evans-Polanyi principle for molecular dynamics trajectories and its implications for global optimization.
• Blood clearance of ICRF 159 (NSC-129943).
• Effect of the Plant Product Croton Oil on the in vivo Incorporation of 3H-Thymidine. Evidence for a Pronounced Inhibition in the Thymus.
• Examination of 20 Bacillus species by crossed immunoelectrophoresis under taxonomic aspects.
• Genetic differentiation across a latitudinal gradient in two co-occurring butterfly species: revealing population differences in a context of climate change.
• Hospitalist performance of cardiac hand-carried ultrasound after focused training.
• In vitro binding of Pasteurella multocida cell wall preparations to tracheal mucus of cattle and swine and to a tracheal epithel cell wall preparation of cattle.
• Inhibition of metastatic spread by I.C.R.F. 159: selective deletion of a malignant characteristic.
• Metastases and the normalization of tumour blood vessels by ICRF 159: a new type of drug action.
• Methylphenidate improves performance on the radial arm maze in periadolescent rats.
• Multifold features determine linear equation for automatic spike detection applying neural nin interictal ECoG.
• Pigment formation from tryptamine and 5-hydroxytryptamine in tissues; a contribution to the histochemistry of amine oxidase.
• Predictors of mortality and length of stay for neonates admitted to children's hospital neonatal intensive care units.
• Represent the batches 2 of strain NCTC 3991 and NCTC 3992 B. coagulans?
• Species identification and serotyping (capsular antigen) of Pasteurella strains from sheep flocks in south Germany and in Syria.
• Spectroscopic methods for the determination of protein interactions.
• The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba.
• [A simple method to monitor COPD progression]
• [Electron microscopic studies of mucosal extirpates of rabbits after after in vitro contact with Pasteurella multocida subsp. multocida strains]
• [First trial of pre-treatment with pacatal in inactin-ether narcosis in gynecology.]
• [INTRAUTERINE CAUTERY FOR HEMOSTASIS.]
• [Immunity of the skin--infection and percutaneous immunization of rabbits with E. coli ATCC 13676]
• [Not Available.]
• [Occurrence and properties of enterotoxigenic Escherichia coli strains from young dogs with enteritis]
• [One-year follow-up of TSH level and thyroid volume in patients with bone marrow or peripheral blood hematopoietic stem cell transplantation following chemotherapy]
• [Plasmid-mediated pathogenicity factors of Yersinia enterocolitica from the epidemiological viewpoint]
• [Thrombotic thrombocytopenic purpura in a patient with systemic lupus erythematosus successfully treated with plasma exchange and corticosteroids]