The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis.

The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis. Abstract Text:

Li Tian,Dean DellaPenna,Richard A Dixon,

Plastoquinone plays critical roles in photosynthesis, chlororespiration and carotenoid biosynthesis. The previously isolated pds2 mutant from Arabidopsis was deficient in tocopherol and plastoquinone accumulation, and the biochemical phenotype of this mutant could not be reversed by externally applied homogentisate, suggesting a later step in tocopherol and/or plastoquinone biosynthesis had been disrupted. Recently, the protein encoded by At3g11950 (AtHST) was shown to condense homogentisate with solanesyl diphosphate (SDP), the substrate for plastoquinone synthesis, but not phytyl diphosphate (PDP), the substrate for tocopherol biosynthesis. We have sequenced the AtHST allele in the pds2 mutant background and identified an in-frame 6 bp (2 aa) deletion in the gene. The pds2 mutation could be functionally complemented by constitutive expression of AtHST, demonstrating that the molecular basis for the pds2 mutation is this 6 bp-lesion in the AtHST gene. Confocal microscopy of EGFP tagged AtHST suggested that AtHST is localized to the chloroplast envelope, supporting the hypothesis that plastoquinone synthesis occurs in the plastid.

The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis. Publishing Authors By Initials

L Tian,D DellaPenna,RA Dixon,

For similar genetic processes: mutagenesis: sequence deletion research abstracts see: genetic processes: mutagenesis: sequence deletion research

PUBMED ID PMID:

MEDLINE DATE:

The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Planta

VOLUME: 226

Page Numbers: 1067-73

Journal Abbreviation: Planta

ISSN: 0032-0935

DAY: 14

MONTH: 06

YEAR: 2007

The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 1250576

The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis. Keywords Mesh Terms:

KEYWORDS: Sequence Deletion

MESH TERMS: metabolism

Chemical & Substance for Abstract: The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis. Information

Substance Name: homogentisate solanesyltransferase, Arab

Registry Number: EC 2.5.1.-

Grant and Affiliation Information for The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis.

AFFILIATION: Plant Biology Division, The Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, OK 73401, USA.

Country: Germany

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Planta

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis Related Publications

• A population-based needs assessment for mental health services.
• Adherence rates with infliximab therapy in Crohn's disease.
• Aromatase inhibitors--gene discovery.
• Cloning and characterization of a cDNA encoding walleye (Sander vitreum) beta-2 microglobulin.
• Delayed increase of tyrosine hydroxylase expression in rat nigrostriatal system after traumatic brain injury.
• Depressive symptoms, cardiovascular risk, and diabetes self-care strategies in African American women with type 2 diabetes.
• Embolic protection of saphenous vein graft percutaneous interventions.
• Gender associations with chronic methylphenidate treatment and behavioral performance following experimental traumatic brain injury.
• Heats of formation and singlet-triplet separations of hydroxymethylene and 1-hydroxyethylidene.
• Immunopathogenicity and oncogenicity of murine leukemia viruses. II. Infection of mice and rats with Scripps leukemia virus.
• Impact of patients' socioeconomic status on the distance travelled for hospital admission in the English National Health Service.
• Influence of salinity and fish species on PAH uptake from dispersed crude oil.
• Interactions of bacterial effector proteins with host proteins.
• Interactive effects of metals in mixtures on bioaccumulation in the amphipod Hyalella azteca.
• Molecular epidemiology of African swine fever virus studied by analysis of four variable genome regions.
• Predicting the energy of the water exchange reaction and free energy of solvation for the uranyl ion in aqueous solution.
• Ps14 factors influencing the timing of the exit procedure for obstructing fetal neck masses.
• Radiographic texture analysis of densitometer-generated calcaneus images differentiates postmenopausal women with and without fractures.
• Reliability of spot test kits for detecting lead in household dust.
• Sex and genetic associations with cerebrospinal fluid dopamine and metabolite production after severe traumatic brain injury.
• Site-isolated base- and acid-mediated Michael-initiated cyclization cascades.
• Special issue: membranes.
• Stimulatory and inhibitory effects of genistein on human uterine leiomyoma cell proliferation are influenced by the concentration.
• The cup is both half empty and half full.
• The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster.
• The participation of the Na+-Ca2+ exchanger in primary cardiac myofibroblast migration, contraction, and proliferation.
• The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis.
• The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease.
• The structure of acetyldihydrolipoic acid.
• Who should lead?