The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme.

The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme. Research Abstract Details 

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The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme. Abstract Text:

Yoshiya Ikawa,Kenta Sasaki,Hiroyuki Tominaga,Tan Inoue,

The P5 or P7 extensions in the group I intron ribozyme serve as "modular activator units" by stabilizing the conserved core of the ribozyme. The P5 extension of a group IC1 intron was introduced to a barely active group IA2 intron lacking its original P7 extension. The inserted P5 extension significantly activated the chimeric construct. Because the CYT-18 protein factor is also known to activate mutant group IA2 and IC1 introns lacking their P7 and P5 extensions, respectively, the RNA and protein activator units function in an analogous manner.

The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme. Publishing Authors By Initials

Y Ikawa,K Sasaki,H Tominaga,T Inoue,

For similar animals: invertebrates: protozoa: ciliophora: oligohymenophorea: hymenostomatida: tetrahymenina: tetrahymena research abstracts see: animals: invertebrates: protozoa: ciliophora: oligohymenophorea: hymenostomatida: tetrahymenina: tetrahymena research

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The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 133

Page Numbers: 665-70

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: May

YEAR: 2003

The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376600

The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme. Keywords Mesh Terms:

KEYWORDS: Tetrahymena

MESH TERMS: genetics

Chemical & Substance for Abstract: The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme. Information

Substance Name: Magnesium

Registry Number: 7439-95-4

Grant and Affiliation Information for The P5 activator of a group IC ribozyme can replace the P7.1/7.2 activator of a group IA ribozyme.

AFFILIATION: Graduate School of Biostudies, Kyoto University, Kyoto 606-8502, Japan.

Country: Japan

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MEDLINETA: J Biochem

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