[The observation of palatopharyngeal histopathologic characteristic on the patients with obstructive sleep apnea-hypopnea syndrome]

[The observation of palatopharyngeal histopathologic characteristic on the patients with obstructive sleep apnea-hypopnea syndrome] Research Abstract Details 

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[The observation of palatopharyngeal histopathologic characteristic on the patients with obstructive sleep apnea-hypopnea syndrome] Abstract Text:

Rongrong Liu,Changyou Ji,

OBJECTIVE: To observe the histopathologic characteristic of the palatopharyngeal tissue and study the effect of ectopic accumulation of lipid on the pathogenesis and development of OSAHS. METHOD: Thirty-eight cases were selected from the patients in hospital and divided into two groups. Each group had 19 cases, coupled according to Body Mass Index (BMI). HE staining, Oil red O lipid staining and the electro microscope technology were used to observe the pathologic characteristic of the palatopharyngeal tissue, especially the ectopic accumulation of lipid. RESULT:There existed obvious fatty infiltration in the palatopharyngeal tissue of OSAHS patients, and the type of the minor salivary glands changed. The ultrastructure showed the corresponding changes and the cellular anoxic changes. CONCLUSION: Fatty infiltration in the palatopharyngeal tissue of OSAHS patients may play an important role in the pharyngeal airway sinking during sleep. There is a closely correlated between fatty infiltration and the pathogenesis and development of OSAHS.

[The observation of palatopharyngeal histopathologic characteristic on the patients with obstructive sleep apnea-hypopnea syndrome] Publishing Authors By Initials

R Liu,C Ji,

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[The observation of palatopharyngeal histopathologic characteristic on the patients with obstructive sleep apnea-hypopnea syndrome] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Lin chuang er bi yan hou ke za zhi = Journal of cl

VOLUME: 20

Page Numbers: 388-90

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ISSN: 1001-1781

DAY: 13

MONTH: May

YEAR: 2006

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LANGUAGE: chi

NlmUniqueID: 9426080

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AFFILIATION: Department of Otolaryngology-Head and Neck Surgery, Daping Hospital of the Third Military Medical University, Chonqing, China. rongronglin123@126.com

Country: China

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MEDLINETA: Lin Chuang Er Bi Yan Hou Ke Za

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