The neurobiology of treatment response to antidepressants and mood stabilizing medications.

The neurobiology of treatment response to antidepressants and mood stabilizing medications. Research Abstract Details 

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The neurobiology of treatment response to antidepressants and mood stabilizing medications. Abstract Text:

As the neurobiology of mood disorders and the mechanisms of action of antidepressant drugs continue to be elucidated, there has been a shift in emphasis from changes in neurotransmitter release and metabolism to regulation of gene expression and neuroprotection. Evidence from animal studies suggests that drug therapy may act on specific transcription factors and target genes that regulate processes such as neuroprotection and neuronal survival. Clinical studies consistently identify changes in prefrontal cortex, hippocampus and amygdala that may be related to the course of illness and may be prevented with successful treatment. Together, these findings suggest that clinically relevant neurobiological correlations may ultimately be identified in patients who respond and remit to treatment. With these and future advances in the neuroscience of psychiatry, it may be possible to identify biological markers that will help in decisions about specific treatments for an individual patient.

The neurobiology of treatment response to antidepressants and mood stabilizing medications. Publishing Authors By Initials

For similar proteins: dna-binding proteins: trans-activators research abstracts see: proteins: dna-binding proteins: trans-activators research

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The neurobiology of treatment response to antidepressants and mood stabilizing medications. Journal Published:

PUBLICATION TYPE: Review

Journal: Journal of psychiatry & neuroscience : JPN

VOLUME: 27

Page Numbers: 260-5

Journal Abbreviation: J Psychiatry Neurosci

ISSN: 1180-4882

DAY: 6

MONTH: Jul

YEAR: 2002

The neurobiology of treatment response to antidepressants and mood stabilizing medications. Information

Number of References: 33

LANGUAGE: eng

NlmUniqueID: 9107859

The neurobiology of treatment response to antidepressants and mood stabilizing medications. Keywords Mesh Terms:

KEYWORDS: Trans-Activators

MESH TERMS: metabolism

Chemical & Substance for Abstract: The neurobiology of treatment response to antidepressants and mood stabilizing medications. Information

Substance Name: Adenylate Cyclase

Registry Number: EC 4.6.1.1

Grant and Affiliation Information for The neurobiology of treatment response to antidepressants and mood stabilizing medications.

AFFILIATION: Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1200 Main St. W, Hamilton, ON L8N 3Z5. youngt@mcmaster.ca

Country: Canada

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MEDLINETA: J Psychiatry Neurosci

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