The National Asthma Campaign Manchester Asthma and Allergy Study.

The National Asthma Campaign Manchester Asthma and Allergy Study. Research Abstract Details 

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The National Asthma Campaign Manchester Asthma and Allergy Study. Abstract Text:

The NACManchester Asthma and Allergy Study is a prospective study of the development of asthma and allergies in childhood. The subjects (995 children at age 3 years) were recruited in utero by screening parents in the antenatal clinic using skin prick testing and a questionnaire regarding allergic diseases. Children were assigned to risk groups according to parental atopic status (high risk, both parents atopic; medium risk, one parent atopic; low risk, neither parent atopic). A subgroup of those at high risk (with no pets in the home) was randomized to stringent environmental control (allergen impermeable covers for the parental and infant bed, hot washing of bedding weekly, HEPA vacuum cleaner, hard floor for the nursery), and the remainder followed a normal regime. The children have been followed prospectively. The environmental influences are very clearly defined. Measurements of environmental exposures include levels of house dust mite; cat and dog allergens during pregnancy and early life; pet ownership and exposure; childcare arrangements; number of siblings; vaccination uptake; thorough dietary questionnaire; and endotoxin exposure. Further unique objective outcome in the cohort is the assessment of lung function in preschool children using specific airways resistance, which at age 3 years clearly reflects both genetic and environmental influences.

The National Asthma Campaign Manchester Asthma and Allergy Study. Publishing Authors By Initials

For similar investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research

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The National Asthma Campaign Manchester Asthma and Allergy Study. Journal Published:

PUBLICATION TYPE: Review

Journal: Pediatric allergy and immunology : official public

VOLUME: 13 Suppl 15

Page Numbers: 32-7

Journal Abbreviation: Pediatr Allergy Immunol

ISSN: 0905-6157

DAY: 28

MONTH: 05

YEAR: 2002

The National Asthma Campaign Manchester Asthma and Allergy Study. Information

Number of References: 8

LANGUAGE: eng

NlmUniqueID: 9106718

The National Asthma Campaign Manchester Asthma and Allergy Study. Keywords Mesh Terms:

KEYWORDS: Risk Factors

MESH TERMS: prevention & control

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Grant and Affiliation Information for The National Asthma Campaign Manchester Asthma and Allergy Study.

AFFILIATION: North West Lung Centre, Wythenshawe Hospital, UK. acustovic@fs1.with.man.ac.uk

Country: England

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MEDLINETA: Pediatr Allergy Immunol

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