The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures.

The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures. Research Abstract Details 

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The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures. Abstract Text:

Thomas J Carmody,A John Rush,Ira Bernstein,Diane Warden,Stephen Brannan,Daniel Burnham,Ada Woo,Madhukar H Trivedi,Thomas J Carmody,A John Rush,Ira Bernstein,Diane Warden,Stephen Brannan,Daniel Burnham,Ada Woo,Madhukar H Trivedi,

The 17-item Hamilton Rating Scale for Depression (HRSD(17)) and the Montgomery Asberg Depression Rating Scale (MADRS) are two widely used clinician-rated symptom scales. A 6-item version of the HRSD (HRSD(6)) was created by Bech to address the psychometric limitations of the HRSD(17). The psychometric properties of these measures were compared using classical test theory (CTT) and item response theory (IRT) methods. IRT methods were used to equate total scores on any two scales. Data from two distinctly different outpatient studies of nonpsychotic major depression: a 12-month study of highly treatment-resistant patients (n=233) and an 8-week acute phase drug treatment trial (n=985) were used for robustness of results. MADRS and HRSD(6) items generally contributed more to the measurement of depression than HRSD(17) items as shown by higher item-total correlations and higher IRT slope parameters. The MADRS and HRSD(6) were unifactorial while the HRSD(17) contained 2 factors. The MADRS showed about twice the precision in estimating depression as either the HRSD(17) or HRSD(6) for average severity of depression. An HRSD(17) of 7 corresponded to an 8 or 9 on the MADRS and 4 on the HRSD(6). The MADRS would be superior to the HRSD(17) in the conduct of clinical trials.

The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures. Publishing Authors By Initials

TJ Carmody,AJ Rush,I Bernstein,D Warden,S Brannan,D Burnham,A Woo,MH Trivedi,TJ Carmody,AJ Rush,I Bernstein,D Warden,S Brannan,D Burnham,A Woo,MH Trivedi,

For similar natural sciences: weights and measures research abstracts see: natural sciences: weights and measures research

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MEDLINE DATE:

The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: European neuropsychopharmacology : the journal of

VOLUME: 16

Page Numbers: 601-11

Journal Abbreviation:

ISSN: 0924-977X

DAY: 12

MONTH: 06

YEAR: 2006

The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9111390

The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures. Keywords Mesh Terms:

KEYWORDS: Weights and Measures

MESH TERMS: physiopathology

Chemical & Substance for Abstract: The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures. Information

Substance Name: Antidepressive Agents

Registry Number: 0

Grant and Affiliation Information for The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures.

AFFILIATION: Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd. Dallas, TX 75390-9086, United States. Thomas.Carmody@UTSouthwestern.edu

Country: Netherlands

AGENCY: United States NIMH

GRANT: MH-68852

ACRONYM: MH

MEDLINETA: Eur Neuropsychopharmacol

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