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[The model of mouse lung tumor short-term induction test for assaying the carcinogencity induced by extracts of birch wood dust]

[The model of mouse lung tumor short-term induction test for assaying the carcinogencity induced by extracts of birch wood dust] Research Abstract Details 

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  • [The model of mouse lung tumor short-term induction test for assaying the carcinogencity induced by extracts of birch wood dust] Abstract Text:

    peng hePeng He,desheng wuDesheng Wu,qinan dongQinan Dong,

    OBJECTIVE: To assay the carcinogencity of water and organic extracts of birch wood dust. METHODS: One stage and two stage model of mouse lung tumor by short-term induction test were used. RESULTS: In the one stage experiment, no significant difference of the incidence of mice lung tumors was observed between different dosage groups of water extracts and organic extracts. In the two stage experiment, the tumor incidence and the average number of tumor per mouse in three dosage groups treated with the water extracts(1, 2, 4 g/kg) were 4.08% and 0.04, 8.33% and 0.15, 14.30% and 0.24 respectively with dose increment. There was a significant dose-response relationship between them(P < 0.05), and the tumor incidence and the average number of tumor per mouse in 4 g/kg group were significantly higher than those in the control group and 1 g/kg group and its one stage group(P < 0.05). The tumor incidence and the average number of tumor per mouse induced by organic extracts were higher with increasing dose, but no significant difference among groups was found (P > 0.05). CONCLUSION: Both extracts of birch wood dust may be initiators, and carcinogenic effect of the water extract is stronger than that of the organic extract.

    [The model of mouse lung tumor short-term induction test for assaying the carcinogencity induced by extracts of birch wood dust] Publishing Authors By Initials

    p heP He,d wuD Wu,q dongQ Dong,

    For similar abstracts research abstracts see: abstracts research

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    [The model of mouse lung tumor short-term induction test for assaying the carcinogencity induced by extracts of birch wood dust] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Z

    VOLUME: 20

    Page Numbers: 116-8

    Journal Abbreviation: Zhonghua Lao Dong Wei Sheng Zh

    ISSN: 1001-9391

    DAY: 25

    MONTH: Apr

    YEAR: 2002

    [The model of mouse lung tumor short-term induction test for assaying the carcinogencity induced by extracts of birch wood dust] Information

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    LANGUAGE: chi

    NlmUniqueID: 8410840

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    Grant and Affiliation Information for [The model of mouse lung tumor short-term induction test for assaying the carcinogencity induced by extracts of birch wood dust]

    AFFILIATION: School of Huaxi Public Health, Sichuan University, Chengdu 610041, China.

    Country: China

    China Research PublicationChina Research Publication

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    MEDLINETA: Zhonghua Lao Dong Wei Sheng Zh

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