The mitotic spindle apparatus has attracted the attention of cell biologists for decades. Whereas the main function of this microtubule-based system is to segregate chromosomes, spindle morphogenesis and chromosome segregation must also coordinate with the segregation of the whole cell. The finding that RanGTPase stimulates the assembly of a lamin B-containing membranous matrix in mitosis(1) may provide a connection between the segregation of mitotic chromosomes and the partitioning of membrane systems during cell division.
The mitotic spindle matrix: a fibro-membranous lamin connection. Publishing Authors By Initials
The mitotic spindle matrix: a fibro-membranous lamin connection. Journal Published:
PUBLICATION TYPE: Review
Journal: Cell cycle (Georgetown, Tex.)
VOLUME: 5
Page Numbers: 2345-7
Journal Abbreviation: Cell Cycle
ISSN: 1551-4005
DAY: 16
MONTH: 10
YEAR: 2006
The mitotic spindle matrix: a fibro-membranous lamin connection. Information
Number of References: 26
LANGUAGE: eng
NlmUniqueID: 101137841
The mitotic spindle matrix: a fibro-membranous lamin connection. Keywords Mesh Terms:
KEYWORDS: ran GTP-Binding Protein
MESH TERMS: physiology
Chemical & Substance for Abstract: The mitotic spindle matrix: a fibro-membranous lamin connection. Information
Substance Name: ran GTP-Binding Protein
Registry Number: EC 3.6.5.2
Grant and Affiliation Information for The mitotic spindle matrix: a fibro-membranous lamin connection.
AFFILIATION: Department of Embryology, Carnegie Institution of Washington and Howard Hughes Medical Institute, Baltimore, Maryland 21218, USA. zheng@ciwemb.edu
Country: United States
AGENCY: United States NIGMS
GRANT: GM56312
ACRONYM: GM
MEDLINETA: Cell Cycle
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