[The metabolic syndrome and bone health. The Relationship Between Lipid and Glucose Metabolism and Bone Mineral Metabolism : Pleiotropic effects of therapeutic agents for diabetes and hyperlipidemia.]

[The metabolic syndrome and bone health. The Relationship Between Lipid and Glucose Metabolism and Bone Mineral Metabolism : Pleiotropic effects of therapeutic agents for diabetes and hyperlipidemia.] Research Abstract Details 

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[The metabolic syndrome and bone health. The Relationship Between Lipid and Glucose Metabolism and Bone Mineral Metabolism : Pleiotropic effects of therapeutic agents for diabetes and hyperlipidemia.] Abstract Text:

Bone mineral metabolism and bone remodeling involve a variety of molecules, for instance, bone morphogenetic proteins (BMPs) , fibroblast growth factors (FGFs) , insulin growth factors (IGFs) , interleukin-1 (IL-1) , prostagrandin E(2) (PGE(2)) , and tumor necrosis factor-alpha (TNF-alpha) . Most of them are also involved in lipid and glucose metabolism. Recent in vitro and in vivo studies have reported that therapeutic agents for diabetes and hyperlipidemia, such as insulin, thiazolidinediones, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have pleiotropic effects on bone mineral metabolism. These agents may be useful tools for treatment of bone and mineral disorders.

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[The metabolic syndrome and bone health. The Relationship Between Lipid and Glucose Metabolism and Bone Mineral Metabolism : Pleiotropic effects of therapeutic agents for diabetes and hyperlipidemia.] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical calcium

VOLUME: 18

Page Numbers: 671-6

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ISSN: 0917-5857

DAY: 30

MONTH: May

YEAR: 2008

[The metabolic syndrome and bone health. The Relationship Between Lipid and Glucose Metabolism and Bone Mineral Metabolism : Pleiotropic effects of therapeutic agents for diabetes and hyperlipidemia.] Information

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LANGUAGE: jpn

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AFFILIATION: Kobe University School of Medicine, Division of Nephrology and Kidney Center.

Country: Japan

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MEDLINETA: Clin Calcium

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