[The influence of temperature on the protein expression of human lung cancer cell line A549]

[The influence of temperature on the protein expression of human lung cancer cell line A549] Research Abstract Details 

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[The influence of temperature on the protein expression of human lung cancer cell line A549] Abstract Text:

Zi Jun Chen,San Ying Wang,Jing An Chen,Xuan Xian Peng,

The study on proteome of human cancer is helpful to explain its pathogenesis and make good effect on its prevention and cure. We compared the 2-DE maps of whole proteins of human lung cancer line A549 at 37 degrees C, 42 degrees C and 45 degrees C for the purpose of studying the expression of its heat shock proteins. Three temperature-sensitive differential spots were obtained and named as P1, P2, P3, respectively. Analyzed by MALDI-TOF-MS and Peptident software searched in the SWISS-PROT database, the three differential proteins were elementarily identified. P1 matches with two proteins belong to the Aldo-keto reductase family, P2 may be a new protein and P3 is Zinc finger protein 11A.

[The influence of temperature on the protein expression of human lung cancer cell line A549] Publishing Authors By Initials

ZJ Chen,SY Wang,JA Chen,XX Peng,

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[The influence of temperature on the protein expression of human lung cancer cell line A549] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Shi yan sheng wu xue bao

VOLUME: 35

Page Numbers: 179-83

Journal Abbreviation: Shi Yan Sheng Wu Xue Bao

ISSN: 0001-5334

DAY: 3

MONTH: Sep

YEAR: 2002

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LANGUAGE: chi

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AFFILIATION: The Key Laboratory of Education Ministry for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, Xiamen 361005.

Country: China

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MEDLINETA: Shi Yan Sheng Wu Xue Bao

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