The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer.

The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer. Abstract Text:

M R Zeiderman,G Gowland,B Peel,M J McMahon,

The influence of short-term pre-operative intravenous nutrition (IVN) upon protein synthesis in human liver and skeletal muscle was investigated in 30 patients with weight loss (>5 kg in preceding 3 months) who underwent resection of a neoplasm of the gastrointestinal tract. Patients were randomised to receive a normal hospital diet (HD group) or a hospital diet supplemented by intravenous nutrition (IVN groups; 0.18 gN/kg/24h as FreAmine III; 126kJ/24h as glucose) for either 3 (IVN(3)) or 7 days (IVN(7)) Nutritional assessment was undertaken by measurement of anthropometric, biochemical and immunological indices. In addition, the rates of protein synthesis in biopsies of liver and skeletal muscle, which were obtained at operation, were determined in vitro from the incorporation into protein of (14)C-leucine. Patients who received a hospital diet only (HD group) were in negative energy balance and continued to lose weight during the pre-operative period. The imbalance between caloric intake and expenditure was met from endogenous fuel stores with a reduction in fat-free mass and arm muscle area. Patients who received IVN maintained body weight and fat-free mass and had higher rates of protein synthesis in liver and skeletal muscle. In addition there was an increase in the plasma concentrations of prealbumin, haptoglobin and complement C3 together with a rise in the concentrations of the circulating immunoglobulins IgM and IgA. The majority of these changes occurred after only 3 days of IVN.

The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer. Publishing Authors By Initials

MR Zeiderman,G Gowland,B Peel,MJ McMahon,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical nutrition (Edinburgh, Scotland)

VOLUME: 10

Page Numbers: 213-21

Journal Abbreviation:

ISSN: 0261-5614

DAY: 14

MONTH: Aug

YEAR: 1991

The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8309603

The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer.

AFFILIATION: University Department of Surgery General Infirmary, Leeds, UK.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Clin Nutr

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer Related Publications

• A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway.
• A randomised study of the effects of osmolality and heparin with hydrocortisone on thrombophlebitis in peripheral intravenous nutrition.
• Acute and Chronic Effects of Ramelteon in Rhesus Monkeys (Macaca mulatta): Dependence Liability Studies.
• Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth.
• Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1.
• Circadian organization of the mammalian retina.
• Coexistence of muscarinic long-term depression with electrically induced long-term potentiation and depression at CA3-CA1 synapses.
• Computer and internet access for long-term care residents: perceived benefits and barriers.
• Constant light disrupts the developing mouse biological clock.
• Correspondence section.
• Determining fall direction and impact location for various disturbances and gait speeds using the articulated total body model.
• Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain.
• Embolisation of silicone rubber catheters used for intravenous feeding; a preventable complication.
• Enhanced nutty flavor formation in cheddar cheese made with a malty Lactococcus lactis adjunct culture.
• Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling.
• Fine bore silicone rubber and polyurethane catheters for the delivery of complete intravenous nutrition via a peripheral vein.
• Functional heterogeneity of retinal dopaminergic neurons underlying their multiple roles in vision.
• High-pressure powder diffraction on synchrotron sources.
• Modulation of A-type potassium currents in retinal horizontal cells by extracellular calcium and zinc.
• Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite.
• Observation and modelling of preferred orientation in two-dimensional powder patterns.
• Patient safety knowledge and its determinants in medical trainees.
• Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature.
• The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.
• The influence of short-term pre-operative intravenous nutrition upon anthropometric variables, protein synthesis and immunological indices in patients with gastrointestinal cancer.
• The role of objective measurement of skeletal muscle function in the pre-operative patient.
• Treatment of erectile dysfunction with chronic dosing of tadalafil.
• Web-based education in systems-based practice: a randomized trial.
• What is familial about familial bipolar disorder? Resemblance among relatives across a broad spectrum of phenotypic characteristics.
• Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development.