The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir.

The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir. Research Abstract Details 

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The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir. Abstract Text:

Regina ,Tatiana Michelon, Wurdig,Iara Fagundes,Sadi Schio,Leticia Sanchez, Camargo,Teresa C Sukkienik,Alessandro C Pasqualotto,Jorge Neumann,Regina Schröeder,Tatiana Michelon,João Wurdig,Iara Fagundes,Sadi Schio,Leticia Sanchez,José J Camargo,Teresa C Sukkienik,Alessandro C Pasqualotto,Jorge Neumann,

The best strategy for control of cytomegalovirus (CMV) infection in lung transplant patients is still not determined. The aim of this study was to document the incidence of CMV infection in a cohort of lung transplant recipients under universal prophylaxis with intravenous ganciclovir. All patients received immunosuppressive regimens consisting of cyclosporine, azathioprine, and prednisone. Regardless of CMV serostatus, intravenous ganciclovir was prescribed for every patient in the first 3 months post-transplantation. CMV infection was defined as the detection of CMV pp65 in leukocytes. Eighty-two lung transplant patients were included over a 5-year period. The incidence of CMV infection in the first year post-transplantation was 68.3%, occurring after a median length of 114 days (range, 26-343 days). This study revealed a high incidence of CMV infection in the first year following lung transplantation despite prolonged universal ganciclovir prophylaxis.

The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir. Publishing Authors By Initials

R ,T Michelon,J Wurdig,I Fagundes,S Schio,L Sanchez,JJ Camargo,TC Sukkienik,AC Pasqualotto,J Neumann,R Schröeder,T Michelon,J Wurdig,I Fagundes,S Schio,L Sanchez,JJ Camargo,TC Sukkienik,AC Pasqualotto,J Neumann,

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The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The Brazilian journal of infectious diseases : an

VOLUME: 11

Page Numbers: 212-4

Journal Abbreviation: Braz J Infect Dis

ISSN: 1413-8670

DAY: 12

MONTH: Apr

YEAR: 2007

The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir. Information

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LANGUAGE: eng

NlmUniqueID: 9812937

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AFFILIATION: Laboratory of Transplant Immunology, Santa Casa Complexo Hospitalar, Avenida Independência 75, 94035-075 Porto Alegre, RS, Brazil. regina@santacasa.tch.br

Country: Brazil

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MEDLINETA: Braz J Infect Dis

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