Chronic kidney disease (CKD) is a known complication of the human immunodeficiency virus (HIV) but outcomes among HIV-infected patients with kidney disease are unknown. We studied a national sample of 202,927 patients with CKD (stage 3 or higher) for death, end-stage renal disease (ESRD) and the mean annual rate of decline in estimated glomerular filtration rate (eGFR) over a median period of 3.8 years. Within this sample, 0.3% of the patients were diagnosed with HIV, 43.5% were diabetic, whereas the remainder had neither disease. In this national CKD cohort, HIV-infected black patients were at higher risk of death, a similar risk for ESRD and loss of eGFR than black patients with diabetes. HIV-infected white patients experienced higher rates of death but a lower risk of ESRD than their counterparts with diabetes. Our results highlight a need to study mortality and mechanisms of ESRD in the HIV infected population.
The impact of HIV on chronic kidney disease outcomes. Publishing Authors By Initials
The impact of HIV on chronic kidney disease outcomes. Journal Published:
PUBLICATION TYPE: Research Support, U.S. Gov't,
Journal: Kidney international
VOLUME: 72
Page Numbers: 1380-7
Journal Abbreviation: Kidney Int.
ISSN: 0085-2538
DAY: 5
MONTH: 09
YEAR: 2007
The impact of HIV on chronic kidney disease outcomes. Information
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LANGUAGE: eng
NlmUniqueID: 323470
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AFFILIATION: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California 94110, USA. andy.choi@ucsf.edu
Country: United States
AGENCY: United States NIDDK
GRANT: T32-DK07219
ACRONYM: DK
MEDLINETA: Kidney Int
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