The immunological paradox of pregnancy.

The immunological paradox of pregnancy. Research Abstract Details 

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The immunological paradox of pregnancy. Abstract Text:

M G Damber,B von Schoultz,T Stigbrand,

During a normal pregnancy the fetus can be regarded as a transplant inside the uterus. The reason why this transplant is not rejected is still unclear. In this work various models for this immunological paradox and recent results within the field of pregnancy immunology are discussed. From an immunological point of view the development of a normal pregnancy is almost impossible. During all stages the embryo can be regarded as a transplant (4), but instead of the expected rejection an intimate parasitic graft - host relationship is established. The sperm has already been shown to be the carrier of transplantation antigens and thus theoretically capable of initiating an immune response. The fertilized egg also carries transplantation antigens on its surface after the first division. Foreign transplantation antigens release in the receiver a cell mediated immune reaction, which normally causes a rejection within some weeks.

The immunological paradox of pregnancy. Publishing Authors By Initials

MG Damber,B von Schoultz,T Stigbrand,

For similar cells: trophoblasts research abstracts see: cells: trophoblasts research

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The immunological paradox of pregnancy. Journal Published:

PUBLICATION TYPE: Review

Journal: Acta obstetricia et gynecologica Scandinavica. Sup

VOLUME: 66

Page Numbers: 39-47

Journal Abbreviation:

ISSN: 0300-8835

DAY: 21

MONTH: 02

YEAR: 1977

The immunological paradox of pregnancy. Information

Number of References: 44

LANGUAGE: eng

NlmUniqueID: 337655

The immunological paradox of pregnancy. Keywords Mesh Terms:

KEYWORDS: Trophoblasts

MESH TERMS: immunology

Chemical & Substance for Abstract: The immunological paradox of pregnancy. Information

Substance Name: Histocompatibility Antigens

Registry Number: 0

Grant and Affiliation Information for The immunological paradox of pregnancy.

AFFILIATION:

Country: SWEDEN

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MEDLINETA: Acta Obstet Gynecol Scand Supp

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