The hormonal pattern of intestinal adaptation. A major role for enteroglucagon.

The hormonal pattern of intestinal adaptation. A major role for enteroglucagon. Research Abstract Details 

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The hormonal pattern of intestinal adaptation. A major role for enteroglucagon. Abstract Text:

S R Bloom,J M Polak,

A number of human diseases with intestinal adaptation have been investigated, including acute infective diarrhoea, intestinal resection, jejuno-ileal bypass, coeliac disease, tropical sprue, chronic pancreatitis and cystic fibrosis. In all, the newly isolated hormone enteroglucagon appeared to be elevated in proportion to the degree of adaptation. In rats after gut resection and cold adaptation, enteroglucagon was also elevated and the degree of elevation correlated closely with the crypt cell production rate (CCPR). Chronic administration of somatostatin suppressed both enteroglucagon and CCPR, while bombesin stimulated both. A crude preparation of enteroglucagon was found to directly stimulate DNA synthesis in enterocyte cultures. It is thus concluded that, at present, the most likely candidate for the humoral component of intestinal adaptation is the hormonal peptide enteroglucagon.

The hormonal pattern of intestinal adaptation. A major role for enteroglucagon. Publishing Authors By Initials

SR Bloom,JM Polak,

For similar animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats research abstracts see: animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats research

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The hormonal pattern of intestinal adaptation. A major role for enteroglucagon. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Scandinavian journal of gastroenterology. Suppleme

VOLUME: 74

Page Numbers: 93-103

Journal Abbreviation: Scand. J. Gastroenterol. Suppl

ISSN: 0085-5928

DAY: 13

MONTH: 02

YEAR: 1982

The hormonal pattern of intestinal adaptation. A major role for enteroglucagon. Information

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LANGUAGE: eng

NlmUniqueID: 437034

The hormonal pattern of intestinal adaptation. A major role for enteroglucagon. Keywords Mesh Terms:

KEYWORDS: Rats

MESH TERMS: therapy

Chemical & Substance for Abstract: The hormonal pattern of intestinal adaptation. A major role for enteroglucagon. Information

Substance Name: Glucagon-Like Peptides

Registry Number: 62340-29-8

Grant and Affiliation Information for The hormonal pattern of intestinal adaptation. A major role for enteroglucagon.

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Country: NORWAY

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MEDLINETA: Scand J Gastroenterol Suppl

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