The histology of the lung in neonates with tricuspid valve disease and gross cardiomegaly due to severe regurgitation.

The histology of the lung in neonates with tricuspid valve disease and gross cardiomegaly due to severe regurgitation. Research Abstract Details 

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The histology of the lung in neonates with tricuspid valve disease and gross cardiomegaly due to severe regurgitation. Abstract Text:

T Tanaka,S Yamaki,T Ohno,A Ozawa,H Kakizawa,K Iinuma,

Lung autopsies from four neonates with Ebstein's anomaly or tricuspid valve dysplasia and gross cardiomegaly were examined. The mean cardiothoracic ratio was 92 +/- 0.5%. The degrees of pulmonary hypoplasia and pulmonary artery muscularization were assessed and were compared with those in lungs from four controls and four patients with diaphragmatic hernias. Lung and body weight ratios and radial alveolar counts, which reflect pulmonary hypoplasia and immaturity, were significantly decreased only in patients with diaphragmatic hernia. The thickness of the medical muscle layer in small pulmonary arteries was greater in patients with diaphragmatic hernia; however, in patients with tricuspid valve disease, it was relatively small. Abnormal vascular muscle extension was seen only in patients with diaphragmatic hernia. In the cases of tricuspid valve disease, although cardiomegaly and lung compression were severe, lung hypoplasia and immaturity were not, and neither abnormal medial thickening nor extension were found. Our results suggest that, at least in full-term infants with tricuspid valve disease, surgical relief of lung compression may improve respiratory function, even if the cardiomegaly is severe.

The histology of the lung in neonates with tricuspid valve disease and gross cardiomegaly due to severe regurgitation. Publishing Authors By Initials

T Tanaka,S Yamaki,T Ohno,A Ozawa,H Kakizawa,K Iinuma,

For similar cardiovascular diseases: heart diseases: heart valve diseases: tricuspid valve insufficiency research abstracts see: cardiovascular diseases: heart diseases: heart valve diseases: tricuspid valve insufficiency research

PUBMED ID PMID:

MEDLINE DATE: 1998 Mar-Apr

The histology of the lung in neonates with tricuspid valve disease and gross cardiomegaly due to severe regurgitation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Pediatric cardiology

VOLUME: 19

Page Numbers: 133-8

Journal Abbreviation: Pediatr Cardiol

ISSN: 0172-0643

DAY: 20

MONTH: 02

YEAR: 2008

The histology of the lung in neonates with tricuspid valve disease and gross cardiomegaly due to severe regurgitation. Information

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LANGUAGE: eng

NlmUniqueID: 8003849

The histology of the lung in neonates with tricuspid valve disease and gross cardiomegaly due to severe regurgitation. Keywords Mesh Terms:

KEYWORDS: Tricuspid Valve Insufficiency

MESH TERMS: pathology

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Grant and Affiliation Information for The histology of the lung in neonates with tricuspid valve disease and gross cardiomegaly due to severe regurgitation.

AFFILIATION: Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan.

Country: UNITED STATES

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MEDLINETA: Pediatr Cardiol

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