The hematopoietic niche: a Drosophila model, at last.

The hematopoietic niche: a Drosophila model, at last. Research Abstract Details 

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The hematopoietic niche: a Drosophila model, at last. Abstract Text:

Crozatier,Joanna Krzemien,Alain Vincent, Crozatier,Joanna Krzemien,Alain Vincent,

The niche provides a specialised microenvironment necessary for maintenance of stem cells in a non differentiated state. While the hematopoietic stem cell (HSC) niche in vertebrates was the first to be recognized, Drosophila niches supporting germline stem cells were characterised first. Recent evidence for the existence of a niche maintaining hematopoietic precursors in Drosophila opens the way to study in vivo the niche/hematopoietic precursors interactions. The availability of a large collection of cell markers, mutants and sophisticated genetic tools makes Drosophila an attractive model for investigating the cellular and molecular mechanisms that are involved in these interactions.

The hematopoietic niche: a Drosophila model, at last. Publishing Authors By Initials

M Crozatier,J Krzemien,A Vincent,M Crozatier,J Krzemien,A Vincent,

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The hematopoietic niche: a Drosophila model, at last. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Cell cycle (Georgetown, Tex.)

VOLUME: 6

Page Numbers: 1443-4

Journal Abbreviation: Cell Cycle

ISSN: 1551-4005

DAY: 7

MONTH: 05

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: Centre de Biologie du Développement, Université Paul Sabatier, Toulouse, France. crozat@cict.fr

Country: United States

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MEDLINETA: Cell Cycle

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