The experimental study of scoliosis in bipedal rat in lathyrism.

The experimental study of scoliosis in bipedal rat in lathyrism. Research Abstract Details 

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The experimental study of scoliosis in bipedal rat in lathyrism. Abstract Text:

H Tanaka,Y Kimura,Y Ujino,

Using Wister albino rats, bipedal rats were prepared; to which semicarbazide at a concentration of 0.075%, 0.05% and 0.025% were given as drinking water and the rats were divided into three groups A, B and C according to such concentrations. Osteolathyrism was caused in this way and the relations between doses as well as the dosing period and the progress of scoliosis were examined roentgenologically and histologically and the following conclusions were obtained. 1. The frequency of occurrence of scoliosis was 82% in the bipedal rats and 13% in the quadrupedal rats (level of significance alpha = 0.001% or less). 2. Primordial top vertebrae were located concentratively in the lower 1/3 of thoracic vertebra. 3. In the primordial curve, those cases showing a right side curve accounted for 76%. 4. After termination of administration of semicarbazide, spontaneous improvement took place only in those cases showing scoliosis of less than 40 degrees. 5. In the author's experimental scoliosis, the static and dynamic condition of posture nearly coincided with those of men in clinical studies. 6. Histological changes were especially marked in the cartilage layer on the vertebral epiphyseal line, being quite diversified.

The experimental study of scoliosis in bipedal rat in lathyrism. Publishing Authors By Initials

H Tanaka,Y Kimura,Y Ujino,

For similar organic chemicals: semicarbazides research abstracts see: organic chemicals: semicarbazides research

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The experimental study of scoliosis in bipedal rat in lathyrism. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of orthopaedic and traumatic surgery. Arc

VOLUME: 101

Page Numbers: 1-27

Journal Abbreviation:

ISSN: 0344-8444

DAY: 21

MONTH: 02

YEAR: 1982

The experimental study of scoliosis in bipedal rat in lathyrism. Information

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LANGUAGE: eng

NlmUniqueID: 7803037

The experimental study of scoliosis in bipedal rat in lathyrism. Keywords Mesh Terms:

KEYWORDS: Semicarbazides

MESH TERMS: radiography

Chemical & Substance for Abstract: The experimental study of scoliosis in bipedal rat in lathyrism. Information

Substance Name: Semicarbazides

Registry Number: 0

Grant and Affiliation Information for The experimental study of scoliosis in bipedal rat in lathyrism.

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Country: GERMANY, WEST

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MEDLINETA: Arch Orthop Trauma Surg

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