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[The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation]

[The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation] Research Abstract Details 

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  • [The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation] Abstract Text:

    m matsuokaM Matsuoka,m imuraM Imura,k higashiK Higashi,m kimuraM Kimura,m okabeM Okabe,t morimotoT Morimoto,i yadaI Yada,s namikawaS Namikawa,h yuasaH Yuasa,m kusagawaM Kusagawa,

    Although various methods for keeping long term good pulmonary function have so far been studied, no reliable method for heart-lung preservation has been established yet. Recently, we aimed at heart-lung preservation using the autoperfusion method and mainly examined pulmonary function after transplantation. After preserving heart-lung organ blocks extracted from mongrel dogs by autoperfusion method, 10 left lungs (preserved for 6.8 +/- 0.8 h) were orthotopically transplanted and combined heart-lung transplantation was performed under extracorporeal circulation using 5 heart-lung grafts (preserved for 7.5 +/- 0.5 h). All of lung-transplanted dogs were alive; preserved lungs showed good gas exchange power from immediately after transplantation. Left lungs on the 3rd day showed normal histological findings and chest X-P also revealed good pneumatization of transplanted lungs. The heart-lung transplantation enabled 4 cases to be free from extracorporeal circulation and arterial blood gas analysis also revealed good results [PO2 396.5 +/- 34.7 mmHg, PCO2 35.5 +/- 6.9 mmHg (FiO2 1.0)]. Lung tissue findings after 6 hours from the above freedom showed slight edema alone. The above results suggested the effectiveness of the autoperfusion method for heart-lung preservation.

    [The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation] Publishing Authors By Initials

    m matsuokaM Matsuoka,m imuraM Imura,k higashiK Higashi,m kimuraM Kimura,m okabeM Okabe,t morimotoT Morimoto,i yadaI Yada,s namikawaS Namikawa,h yuasaH Yuasa,m kusagawaM Kusagawa,

    For similar surgical procedures, operative: postoperative period research abstracts see: surgical procedures, operative: postoperative period research

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    [The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: [Zasshi] [Journal]. Nihon Ky?bu Geka Gakkai

    VOLUME: 38

    Page Numbers: 1442-7

    Journal Abbreviation:

    ISSN: 0369-4739

    DAY: 14

    MONTH: Sep

    YEAR: 1990

    [The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation] Information

    Number of References:

    LANGUAGE: jpn

    NlmUniqueID: 19130180

    [The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation] Keywords Mesh Terms:

    KEYWORDS: Postoperative Period

    MESH TERMS: methods

    Chemical & Substance for Abstract: [The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation] Information

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    Grant and Affiliation Information for [The experimental study for autoperfused heart-lung preservation--evaluation of pulmonary function after transplantation]

    AFFILIATION: Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, Japan.

    Country: JAPAN

    JAPAN Research PublicationJAPAN Research Publication

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    MEDLINETA: Nippon Kyobu Geka Gakkai Zassh

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