The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors.

The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors. Abstract Text:

Takahiro Nakajima,Kazuhiro Yasufuku,Akira Iyoda,Shigetoshi Yoshida,Makoto Suzuki,Yasuo Sekine,Kiyoshi Shibuya,Kenzo Hiroshima,Yukio Nakatani,Takehiko Fujisawa,

OBJECTIVES: Pulmonary metastasectomy is accepted as an effective treatment for properly selected patients with metastatic lung tumors. In such patients, the presence of mediastinal and/or hilar lymph node metastasis is a significant negative prognostic factor. The purpose of this study was to evaluate the usefulness of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the detection of mediastinal and hilar lymph node metastasis in patients with potentially resectable metastatic lung tumors. METHODS: Patients with metastatic lung tumors with radiologically defined mediastinal and/or hilar lymph nodes on chest computed tomographic scans referred to our department for pulmonary resection were retrospectively analyzed. Successful lymph node aspiration was evidenced by the presence of malignant cells or normal lymphocytes. Cytologic and histologic analysis was used to confirm metastasis in surgically resected specimens unless metastasis was proven by EBUS-TBNA. RESULTS: A total of 106 patients were referred for metastasectomy during the study period. EBUS-TBNA was performed in 60 lymph nodes (37 mediastinal and 23 hilar nodes) from 43 patients. Cytologic and/or histologic samples were diagnostic in 41 (95.3%) patients. EBUS-TBNA detected lymph node metastasis in 23 patients. The sensitivity, specificity, and diagnostic accuracy rate of EBUS-TBNA for diagnosis of mediastinal and hilar lymph node metastasis were 92.0%, 100%, and 95.3%, respectively. CONCLUSIONS: EBUS-TBNA is a highly sensitive modality for the evaluation of mediastinal and hilar lymph node metastasis in patients with metastatic lung tumors. EBUS-TBNA allows preoperative histologic as well as cytologic evaluation of mediastinal and hilar lymph nodes.

The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors. Publishing Authors By Initials

T Nakajima,K Yasufuku,A Iyoda,S Yoshida,M Suzuki,Y Sekine,K Shibuya,K Hiroshima,Y Nakatani,T Fujisawa,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The Journal of thoracic and cardiovascular surgery

VOLUME: 134

Page Numbers: 1485-90

Journal Abbreviation: J. Thorac. Cardiovasc. Surg.

ISSN: 1097-685X

DAY: 3

MONTH: Dec

YEAR: 2007

The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376343

The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors.

AFFILIATION: Department of Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Thorac Cardiovasc Surg

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors Related Publications

• A Solitary Metastatic Lung Tumor from Thyroid Papillary Carcinoma Diagnosed by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA): Report of a Case.
• A comparison of clinical features between chlamydial and non-chlamydial urethritis in men negative for gonococcal infection who attended a urological outpatient clinic in Japan.
• A conservative test for multiple comparison based on highly correlated test statistics.
• A novel neuropeptide (FRamide) family identified by a peptidomic approach in Hydra magnipapillata.
• Aberrant methylation of IL-12Rbeta2 gene in lung adenocarcinoma cells is associated with unfavorable prognosis.
• Assessment of gonadotropin therapy in male hypogonadotropic hypogonadism.
• Clinical outcome of surgical management for patients with renal cell carcinoma involving the inferior vena cava.
• Diversity of structural behavior in vertebrate conventional myosins complexed with actin.
• Endobronchial ultrasound-guided transbronchial needle aspiration for the treatment of central airway stenosis caused by a mediastinal cyst.
• Exploratory aspirin resistance trial in healthy Japanese volunteers (J-ART) using platelet aggregation as a measure of thrombogenicity.
• High-Pressure Solution X-ray Scattering of Protein Using a Hydrostatic Cell with Diamond Windows.
• Identification and characterization of CaMKP-N, nuclear calmodulin-dependent protein kinase phosphatase.
• Improved accuracy for predicting the Gleason score of prostate cancer by increasing the number of transrectal biopsy cores.
• Increased testicular 8-hydroxy-2'-deoxyguanosine in patients with varicocele.
• Interactions between Plexin-A2, Plexin-A4, and Semaphorin 6A Control Lamina-Restricted Projection of Hippocampal Mossy Fibers.
• Malignant pheochromocytoma with IVC thrombus.
• Posterior approach for retroperitoneal laparoscopic bilateral native nephrectomy in prone position: initial experience with four cases.
• Radical-scavenging activity of the reaction products of isoeugenol with thiol, thiophenol, mercaptothiazoline or mercaptomethylimidazole using the induction period method.
• Regulation of Ca(2+)/calmodulin-dependent protein kinase kinase alpha by cAMP-dependent protein kinase: I. Biochemical analysis.
• Regulation of Ca(2+)/calmodulin-dependent protein kinase kinase alpha by cAMP-dependent protein kinase: II. Mutational analysis.
• Regulation of the activities of multifunctional Ca2+/calmodulin-dependent protein kinases.
• Significance of lateral biopsy specimens during transrectal ultrasound-guided prostate biopsies in Japanese men.
• Significance of radical cystectomy for bladder cancer in patients over 80 years old.
• Studies on the phosphorylation of protein kinase B by Ca(2+)/calmodulin-dependent protein kinases.
• Substrate specificity of Ca(2+)/calmodulin-dependent protein kinase phosphatase: kinetic studies using synthetic phosphopeptides as model substrates.
• Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer.
• The aboral pore of hydra: evidence that the digestive tract of hydra is a tube not a sac.
• The evaluation of lymph node metastasis by endobronchial ultrasound-guided transbronchial needle aspiration: crucial for selection of surgical candidates with metastatic lung tumors.
• Transurethral drainage for prostatic abscess in a patient with metastatic testicular cancer undergoing systemic chemotherapy.
• Usefulness and problems of the urinary tract infection criteria for evaluating drug efficacy for complicated urinary tract infections.