The efficacy of duloxetine in the treatment of premature ejaculation.

The efficacy of duloxetine in the treatment of premature ejaculation. Research Abstract Details 

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The efficacy of duloxetine in the treatment of premature ejaculation. Abstract Text:

Zahariou Athanasios,Papaioannou Polyanthi,Karagiannis George,

AIM: Though premature ejaculation (PE) has been overshadowed by current attention given to erectile dysfunction, it is the most widespread form of male sexual dysfunction. Delayed or inhibited ejaculation, a known side effect of selective serotonin reuptake inhibitors (SSRIs), has made SSRIs potentially useful in the treatment of this disorder. In the present study, we examined the efficacy of duloxetine, an SSRI, in the treatment of PE. METHOD: The study included 20 married patients diagnosed with PE. The patients were randomly assigned to two groups, duloxetine (group I) and placebo (group II), each consisting of 10 patients. The effects on the ejaculatory function were estimated by the intravaginal ejaculation latency time. All patients were evaluated by using clinical global impression-improvement Scale (CGI-I). RESULTS: The increase in the intravaginal ejaculation latency time in the duloxetine group was statistically significant than that of placebo group. Of group I patients, four (40%) were considered as "very much improved" and four (40%) "much improved" by CGI-I and only one of group II patients (10%) showed "much improved". CONCLUSION: Duloxetine appears to be superior to placebo in the pharmacological treatment of PE when administered on a chronic basis.

The efficacy of duloxetine in the treatment of premature ejaculation. Publishing Authors By Initials

Z Athanasios,P Polyanthi,K George,

For similar diagnosis: prognosis: treatment outcome research abstracts see: diagnosis: prognosis: treatment outcome research

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The efficacy of duloxetine in the treatment of premature ejaculation. Journal Published:

PUBLICATION TYPE: Randomized Controlled Trial

Journal: International urology and nephrology

VOLUME: 39

Page Numbers: 115-8

Journal Abbreviation:

ISSN: 0301-1623

DAY: 28

MONTH: 11

YEAR: 2007

The efficacy of duloxetine in the treatment of premature ejaculation. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 262521

The efficacy of duloxetine in the treatment of premature ejaculation. Keywords Mesh Terms:

KEYWORDS: Treatment Outcome

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: The efficacy of duloxetine in the treatment of premature ejaculation. Information

Substance Name: duloxetine

Registry Number: 116539-58-3

Grant and Affiliation Information for The efficacy of duloxetine in the treatment of premature ejaculation.

AFFILIATION: Urology Department, ELPIS Hospital, 3 Spyridi Street, Volos 38221, Greece. zahariou@otenet.gr

Country: Hungary

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MEDLINETA: Int Urol Nephrol

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