The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches.

The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches. Research Abstract Details 

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The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches. Abstract Text:

T Schnieder,M Lechler,C Epe,S Kuschfeldt,M Stoye,

The efficacy of doramectin treatment on arrested A. caninum larvae during early pregnancy of bitches was examined. Four bitches were percutaneously infected with 20,000 third-stage larvae of A. caninum on the day of conception and treated subcutaneously with 1 mg doramectin per kg body weight on day 30 of pregnancy. Four infected untreated pregnant bitches served as controls. A single application of dormectin substantially reduced the number of somatic larvae in bitches and the number of intestinal stages in bitches and puppies. However, it did not completely prevent lactogenic transmission of A. caninum larvae because five out of 23 puppies from three litters of the treated bitches harboured adult worms in their intestines, two of them shed eggs with the faeces. Although clinical disease did not occur in puppies from treated bitches the efficacy of the treatment was not satisfactory from an epidemiological point of view. Despite the treatment puppies with patent infections contaminated their environment with high numbers of eggs thus producing an intolerable infection risk for dogs and humans. No fetotoxic side-effects of the early treatment with doramectin were seen.

The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches. Publishing Authors By Initials

T Schnieder,M Lechler,C Epe,S Kuschfeldt,M Stoye,

For similar parasitic diseases: pregnancy complications, parasitic research abstracts see: parasitic diseases: pregnancy complications, parasitic research

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The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zentralblatt für Veterinärmedizin. Reihe B. Journa

VOLUME: 43

Page Numbers: 351-6

Journal Abbreviation: Zentralblatt Veterinarmedizin

ISSN: 0514-7166

DAY: 13

MONTH: Aug

YEAR: 1996

The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches. Information

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LANGUAGE: eng

NlmUniqueID: 331325

The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches. Keywords Mesh Terms:

KEYWORDS: Pregnancy Complications, Parasitic

MESH TERMS: veterinary

Chemical & Substance for Abstract: The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches. Information

Substance Name: Ivermectin

Registry Number: 70288-86-7

Grant and Affiliation Information for The efficacy of doramectin on arrested larvae of Ancylostoma caninum in early pregnancy of bitches.

AFFILIATION: Institute of Parasitology, School of Veterinary Medicine, Hannover, Germany.

Country: GERMANY

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MEDLINETA: Zentralbl Veterinarmed B

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