The effects of methyltestosteone on reproductive function in male greyhounds.

The effects of methyltestosteone on reproductive function in male greyhounds. Research Abstract Details 

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The effects of methyltestosteone on reproductive function in male greyhounds. Abstract Text:

J L Freshman,P N Olson,R P Amann,E D Carlson,D C Twedt,R A Bowen,

Oral administration of methyltestosterone (MT) at 50 mg/dog/day to intact adult male greyhounds for 90 d resulted in decreased (P < 0.05) mean daily sperm output and mean testicular length. Additionally, the mean diameter of seminiferous tubules in MT-treated dogs tended to decrease (P = 0.08). Mean concentrations of luteinizing hormone (LH) and follicle stimulating hormone (FSH) and concentrations of testosterone in serum were also decreased or tended to decrease (P = 0.0003 to 0.059) at various sampling periods during MT treatment, suggesting alterations in spermatogenesis resulted from decreased serum concentrations of gonadotropins and steroids. Mean daily sperm output, mean testicular length, mean seminiferous tubule diameter and mean concentrations of FSH in serum were not decreased (P > 0.05) at the end of a 90-d recovery period. However, mean concentrations of serum LH and concentrations of testosterone were still lower (P < 0.05) during five of six and one of six sampling times, respectively, during the recovery period than the pretreatment levels, suggesting a prolonged effect of MT treatment on the pituitary/gonadal axis.

The effects of methyltestosteone on reproductive function in male greyhounds. Publishing Authors By Initials

JL Freshman,PN Olson,RP Amann,ED Carlson,DC Twedt,RA Bowen,

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The effects of methyltestosteone on reproductive function in male greyhounds. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Theriogenology

VOLUME: 33

Page Numbers: 1057-73

Journal Abbreviation: Theriogenology

ISSN: 0093-691X

DAY: 26

MONTH: May

YEAR: 1990

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LANGUAGE: eng

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AFFILIATION: Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences Colorado State University, Fort Collins, CO 80523 USA.

Country: United States

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MEDLINETA: Theriogenology

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