The effects of acute infection on indices of zinc status.

The effects of acute infection on indices of zinc status. Research Abstract Details 

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The effects of acute infection on indices of zinc status. Abstract Text:

H F Goode,J Kelleher,B E Walker,

Various indices of zinc status were assessed in 12 patients with acute urinary tract or chest infections on Day 1 and Day 7 of the infection. Leucocyte counts were raised on Day 1 but had returned to near normal by Day 7. Plasma zinc was decreased on Day 1 in conjunction with depressed plasma albumin concentrations (r = 0.71, p < 0.001) but both had returned to normal by Day 7. Mononuclear cell zinc was raised in all patients on Day 1 compared to Day 7 and control values, but polymorphonuclear cell zinc remained unchanged. However, polymorphonuclear cell alkaline phosphatase activity was grossly increased on Day 1 and correlated with leucocyte count (r = 0.61, p < 0.01). Plasma alkaline phosphatase activity was variable. These results indicate that in patients with infections measurement of plasma mononuclear cell zinc concentration and alkaline phosphatase activity are misleading indicators of zinc status. Polymorphonuclear cell zinc is unaffected by leucocytosis, inflammation and stress and may therefore provide a more reliable index of zinc status in such patients.

The effects of acute infection on indices of zinc status. Publishing Authors By Initials

HF Goode,J Kelleher,BE Walker,

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The effects of acute infection on indices of zinc status. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical nutrition (Edinburgh, Scotland)

VOLUME: 10

Page Numbers: 55-9

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ISSN: 0261-5614

DAY: 14

MONTH: Feb

YEAR: 1991

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LANGUAGE: eng

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AFFILIATION: University of Leeds, Department of Medicine, St. James's University Hospital, Leeds LS9 7TF, UK.

Country: England

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MEDLINETA: Clin Nutr

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