The effect of transcervical uterine manipulations on establishment of uterine infection in mares under the influence of progesterone.

The effect of transcervical uterine manipulations on establishment of uterine infection in mares under the influence of progesterone. Research Abstract Details 

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The effect of transcervical uterine manipulations on establishment of uterine infection in mares under the influence of progesterone. Abstract Text:

A M McDonnell,E D Watson,

Four pony mares were used in a cross-over study to investigate the effect of different treatments on experimentally-induced endometritis. The mares were treated with progesterone to facilitate establishment of uterine infections. They received an intrauterine infusion of Streptococcus zooepidemicus 5 days after the start of progesterone therapy. Five days later, they were treated by intrauterine infusions of 2 g ampicillin in 50 ml sterile water or by sterile water without antibiotic for 3 consecutive days. Prior to infusion of Strep. zooepidemicus , no bacteria were cultured from the uteri of the mares. However, 5 days after infusion of Strep. zooepidemicus and prior to antibiotic therapy, mixed bacterial growths were cultured from endometrial swabbings. After antibiotic therapy, ampicillin-resistant organisms were cultured from endometrial swabbings. Two other progesterone-treated mares received an intrauterine infusion of sterile phosphate buffered saline instead of bacteria. Mixed bacterial cultures were recovered 5 days later from the endometrial swabbings of these mares. It was concluded that the high circulating concentrations of progesterone were probably responsible for the treatment failure and that in clinical situations, therapy involving transcervical manipulations should not be administered when mares are in diestrus.

The effect of transcervical uterine manipulations on establishment of uterine infection in mares under the influence of progesterone. Publishing Authors By Initials

AM McDonnell,ED Watson,

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The effect of transcervical uterine manipulations on establishment of uterine infection in mares under the influence of progesterone. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Theriogenology

VOLUME: 38

Page Numbers: 945-50

Journal Abbreviation: Theriogenology

ISSN: 0093-691X

DAY: 26

MONTH: Nov

YEAR: 1992

The effect of transcervical uterine manipulations on establishment of uterine infection in mares under the influence of progesterone. Information

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LANGUAGE: eng

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Grant and Affiliation Information for The effect of transcervical uterine manipulations on establishment of uterine infection in mares under the influence of progesterone.

AFFILIATION: Department of Veterinary Clinical Studies Royal (Dick) School of Veterinary Studies Veterinary Field Station, Roslin, Midlothian, EH25 9RG, Scotland.

Country: United States

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MEDLINETA: Theriogenology

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