[The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro]

[The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro] Research Abstract Details 

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[The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro] Abstract Text:

J M Jiang,S B Xu,Y C Kong,

OBJECTIVE: To study the effects of Kudingcha (Ilex latifolia Thunb., IL) on the isolated guinea pig tracheal smooth muscle in vitro. METHOD: By obtaining CaCl2 and Histamine accumulative dose-response curves, to observe the influences of IL on the contraction of tracheal strips induced by calcium and some asthmogenic mediators. RESULT: CaCl2 and histamine caused significant contraction of tracheal smooth muscle and pD2 was 3.55 and 5.34 respectively. After incubated with IL, the dose-response curves of CaCl2 and histamine were significantly shifted to the right, and the maximal contractile force was reduced. IL could also inhibit isolated tracheal strip contraction induced by acetylcholine 3 x 10(-6) mol.L-1 and histamine 3 x 10(-6) mol.L-1, and IC50 was 0.16 mg.ml-1 and 0.21 mg.ml-1. CONCLUSION: Kudingcha has significant dilated effects on tracheal smooth muscle.

[The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro] Publishing Authors By Initials

JM Jiang,SB Xu,YC Kong,

For similar respiratory system: trachea research abstracts see: respiratory system: trachea research

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[The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazh

VOLUME: 26

Page Numbers: 853-6

Journal Abbreviation: Zhongguo Zhong Yao Za Zhi

ISSN: 1001-5302

DAY: 6

MONTH: Dec

YEAR: 2001

[The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro] Information

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LANGUAGE: chi

NlmUniqueID: 8913656

[The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro] Keywords Mesh Terms:

KEYWORDS: Trachea

MESH TERMS: drug effects

Chemical & Substance for Abstract: [The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro] Information

Substance Name: Calcium Chloride

Registry Number: 10043-52-4

Grant and Affiliation Information for [The effect of kudingcha (Ilex latifolia Thunb.) on the contraction of isolated guinea-pig tracheal smooth muscle in vitro]

AFFILIATION: Department of Pharmacy, Sun Yat-Sen University, Guangzhou 510275, Guangdong, China.

Country: China

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MEDLINETA: Zhongguo Zhong Yao Za Zhi

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