The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats.

The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats. Research Abstract Details 

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The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats. Abstract Text:

The carcinogenic substance 4-dimethylaminoazobenzene and the non-carcinogen azobenzene were administered orally once a day to male Sprague-Dawley rats over several weeks at an equimolar dosage of 5-10(-5) moles/kg. Their immunological properties were examined in four different tests. The two substances suppress the cellular immune reactions of the rats already during the first month of treatment. The degree of efficiency of the immunosuppressive property decrease with the degree of antigenicity of the test antigen. Even a two-month treatment of the animals with the two substances had no evident influence on antibody formation. Correlations between the immune response and the carcinogenic effect were not demonstrable.

The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats. Publishing Authors By Initials

For similar organic chemicals: amines: aniline compounds: p-dimethylaminoazobenzene research abstracts see: organic chemicals: amines: aniline compounds: p-dimethylaminoazobenzene research

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The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zeitschrift für Krebsforschung und klinische Onkol

VOLUME: 87

Page Numbers: 327-32

Journal Abbreviation:

ISSN: 0084-5353

DAY: 9

MONTH: Dec

YEAR: 1976

The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats. Information

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LANGUAGE: eng

NlmUniqueID: 1276653

The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats. Keywords Mesh Terms:

KEYWORDS: p-Dimethylaminoazobenzene

MESH TERMS: pharmacology

Chemical & Substance for Abstract: The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats. Information

Substance Name: p-Dimethylaminoazobenzene

Registry Number: 60-11-7

Grant and Affiliation Information for The effect of 4-dimethylaminoazobenzene and azobenzene on the immune reaction of male Sprague-Dawley rats.

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Country: GERMANY, WEST

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MEDLINETA: Z Krebsforsch Klin Onkol Cance

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