The effect in vitro of irrigating solutions on intact rat articular cartilage.

The effect in vitro of irrigating solutions on intact rat articular cartilage. Research Abstract Details 

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The effect in vitro of irrigating solutions on intact rat articular cartilage. Abstract Text:

S K Bulstra,R Kuijer,P Eerdmans,A J van der Linden,

Rat patellae were preincubated with culture medium M199 for one hour and then with either fresh culture medium or Ringer's solution, Ringer lactate, Ringer glucose, normal saline or Betadine for another hour. The rate of proteoglycan synthesis in the articular cartilage was then measured by uptake of 35SO4 for the next 16 hours. Cartilage metabolism was inhibited by all of the solutions even after a recovery time of 16 hours. The inhibition was by 5% for Ringer's solution, 10% for Ringer glucose (p < 0.01), 20% for saline and Ringer lactate (p < 0.001) and 55% for Betadine (p < 0.001). Ringer's solution is therefore the best choice for joint irrigation during arthroscopy or other procedures.

The effect in vitro of irrigating solutions on intact rat articular cartilage. Publishing Authors By Initials

SK Bulstra,R Kuijer,P Eerdmans,AJ van der Linden,

For similar pharmaceutical preparations: solutions research abstracts see: pharmaceutical preparations: solutions research

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The effect in vitro of irrigating solutions on intact rat articular cartilage. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of bone and joint surgery. British vol

VOLUME: 76

Page Numbers: 468-70

Journal Abbreviation:

ISSN: 0301-620X

DAY: 14

MONTH: May

YEAR: 1994

The effect in vitro of irrigating solutions on intact rat articular cartilage. Information

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LANGUAGE: eng

NlmUniqueID: 375355

The effect in vitro of irrigating solutions on intact rat articular cartilage. Keywords Mesh Terms:

KEYWORDS: Solutions

MESH TERMS: pharmacology

Chemical & Substance for Abstract: The effect in vitro of irrigating solutions on intact rat articular cartilage. Information

Substance Name: Ringer's solution

Registry Number: 8026-10-6

Grant and Affiliation Information for The effect in vitro of irrigating solutions on intact rat articular cartilage.

AFFILIATION: University Hospital, Maastricht, The Netherlands.

Country: ENGLAND

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MEDLINETA: J Bone Joint Surg Br

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