[The diagnostic and prognostic significance of epithelial blood group isoantigens in carcinomas and polyps of the colon (author's transl)]

[The diagnostic and prognostic significance of epithelial blood group isoantigens in carcinomas and polyps of the colon (author's transl)] Research Abstract Details 

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[The diagnostic and prognostic significance of epithelial blood group isoantigens in carcinomas and polyps of the colon (author's transl)] Abstract Text:

Blood group isoantigens (BG) were detected in carcinomas and polyps of the colon and were related to the degree of differentiation, the histologic type, the age of the patients and the histologic signs of malignancy. 1. BG were found in 60-70% of colon carcinomas regardless of their differentiation. 2. BG-positive carcinomas were less often surrounded by lymphocytes and plasma cells than BG-negative ones. 3. BG were present in colon polyps as mucusassociated and as membrane-associated antigens depending on the differentiation of the cells. Hence, BG-activity can be regarded as additional criterium to assess objectively the differentiation of the tumor cells in a polyp. 4. The percentage of BG-positive polyps increased with dedifferentiation. 5. Polyps with foci of malignant degeneration were consistently BG-positive. 6. Villous polyps contained BG more often than the adenomatous ones. 7. The results support the concept that both villous and adenomatous polyps of the colon are precancerous lesions.

[The diagnostic and prognostic significance of epithelial blood group isoantigens in carcinomas and polyps of the colon (author's transl)] Publishing Authors By Initials

For similar biological factors: antigens: isoantigens research abstracts see: biological factors: antigens: isoantigens research

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[The diagnostic and prognostic significance of epithelial blood group isoantigens in carcinomas and polyps of the colon (author's transl)] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Österreichische Zeitschrift für Onkologie. Austria

VOLUME: 2

Page Numbers: 39-46

Journal Abbreviation:

ISSN: 0377-2004

DAY: 28

MONTH: 02

YEAR: 1975

[The diagnostic and prognostic significance of epithelial blood group isoantigens in carcinomas and polyps of the colon (author's transl)] Information

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LANGUAGE: ger

NlmUniqueID: 7507343

[The diagnostic and prognostic significance of epithelial blood group isoantigens in carcinomas and polyps of the colon (author's transl)] Keywords Mesh Terms:

KEYWORDS: Isoantigens

MESH TERMS: immunology

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Substance Name: Isoantigens

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Country: AUSTRIA

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MEDLINETA: Osterr Z Onkol

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