The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate.

The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate. Research Abstract Details 

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The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate. Abstract Text:

R J Bigsby,R J Rider,G N Blount,

This paper is intended as an overview of the research carried out at Coventry University in the design of a portable artificial kidney system. It was seen that the key to the problem was the reduction in dialysate volume, and so it was decided to develop a prototype that would utilize the regeneration and recirculation of a small volume of dialysate. A prototype system has been produced and used to simulate a dialysis session. Activated carbon was used as a sorbent for the regeneration of the dialysate, circulating in a closed loop. For the purpose of this work, the adsorption of urea was investigated as this is, volumetrically, the major solute to be removed. Peltier effect cooling was used to vary the dialysate temperature down to 2 degrees C, as activated carbon will adsorb greater amounts of urea at lower temperatures. A series of tests was then carried out to investigate the effect of dialysate temperature, flowrate and volume on the amount of urea that could be dialysed. From the experimental results, a model of the system was derived, which made it possible to determine the implications of different operating conditions on the overall mass and size of a portable dialysis system. The output of this model was then used to establish a design specification and produce an optimum design solution for the system.

The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate. Publishing Authors By Initials

RJ Bigsby,RJ Rider,GN Blount,

For similar organic chemicals: urea research abstracts see: organic chemicals: urea research

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The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Proceedings of the Institution of Mechanical Engin

VOLUME: 212

Page Numbers: 373-81

Journal Abbreviation:

ISSN: 0954-4119

DAY: 21

MONTH: 02

YEAR: 1998

The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate. Information

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LANGUAGE: eng

NlmUniqueID: 8908934

The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate. Keywords Mesh Terms:

KEYWORDS: Urea

MESH TERMS: pharmacokinetics

Chemical & Substance for Abstract: The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate. Information

Substance Name: Urea

Registry Number: 57-13-6

Grant and Affiliation Information for The design of an optimized portable artificial kidney system using recirculation and regeneration of dialysate.

AFFILIATION: School of Engineering, Coventry University.

Country: ENGLAND

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MEDLINETA: Proc Inst Mech Eng [H]

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