The biological role of dectin-1 in immune response.

The biological role of dectin-1 in immune response. Research Abstract Details 

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The biological role of dectin-1 in immune response. Abstract Text:

Lina Sun,Yong Zhao,Lina Sun,Yong Zhao,Lina Sun,Yong Zhao,

The identification of antigen-recognizing receptors in the innate immune system significantly helped us to understand the initiation and regulation of the innate immune response. Dectin-1 was recently identified as the most important receptor for beta-glucan. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection. In addition, dectin-1 is involved in the adaptive immune response as well as autoimmune diseases and immune tolerance. In this paper, we will mainly focus on the characteristics of dectin-1 and its biological role in immune response.

The biological role of dectin-1 in immune response. Publishing Authors By Initials

L Sun,Y Zhao,L Sun,Y Zhao,L Sun,Y Zhao,

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The biological role of dectin-1 in immune response. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: International reviews of immunology

VOLUME: 26

Page Numbers: 349-64

Journal Abbreviation: Int. Rev. Immunol.

ISSN: 0883-0185

DAY: 20

MONTH: 11

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 8712260

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AFFILIATION: Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

Country: United States

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MEDLINETA: Int Rev Immunol

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