[The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese]

[The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese] Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

[The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese] Abstract Text:

Lan-qin Chi,Chen Zhang,Bing Luo,Hao-yun Sun,

OBJECTIVE: To ascertain whether the human glucocorticoid receptor (GR) gene polymorphism is associated with cerebral infarction (CI) and essential hypertension (EH) in Chinese. METHODS: This is a case-control study of Chinese DNA samples abstracted from 163 subjects. The samples were analysed by a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) to determine the intron 4 variant of human GR gene. RESULTS: By analysis of the samples from both sexes as a whole, no association was observed between the EH+CI group and control group, and between the CI group and control group. However, by analysis of the samples from the females, weak association was observed between the EH+CI group and control group, and between the CI group and control group; the frequency of allele G was 0.64 for the EH+CI group, 0.69 for CI group and 0.46 for control group. CONCLUSION: The G allele may be a predisposing gene marker, GR gene intron 4 polymorphism contributes to the development of CI in females.

[The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese] Publishing Authors By Initials

LQ Chi,C Zhang,B Luo,HY Sun,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

[The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yix

VOLUME: 20

Page Numbers: 353-6

Journal Abbreviation: Zhonghua Yi Xue Yi Chuan Xue Z

ISSN: 1003-9406

DAY: 6

MONTH: Aug

YEAR: 2003

[The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese] Information

Number of References:

LANGUAGE: chi

NlmUniqueID: 9425197

[The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese] Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: [The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese] Information

Substance Name:

Registry Number:

Grant and Affiliation Information for [The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese]

AFFILIATION: Department of Neurology, Laiyang Central Hospital, Yantai, Shandong, 265200 PR China. LINZHIXD@public.ytptt.sd.cn

Country: China

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Zhonghua Yi Xue Yi Chuan Xue Z

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese Related Publications

• Circadian clock genes oscillate in human peripheral blood mononuclear cells.
• Lumbar spinal fusion with a mineralized collagen matrix and rhBMP-2 in a rabbit model.
• Regulatory peptides modulate ICAM-1 gene expression and NF-kappaB activity in bronchial epithelial cells.
• [A comparative study of EGFR and FGFR-2 expression in fetal and adult skin]
• [A monitoring study of electromyography median frequency on fatigue of erector spinalis in drivers working at high altitude]
• [Achievements in the research on filariasis in China in the past 50 years]
• [An experiment to study the treatment of sarcomas by electroporation]
• [An observation of the effects of Tiopronin on the oxygen free radicals in severely scalded rats receiving delayed fluid resuscitation]
• [Analysis on genetic polymorphism of 14 short tandem repeat loci on chromosome 7p14-15 and 12q13 in Chinese north Hans]
• [Application of noninvasive hemodynamic monitoring in patients with heart failure caused by chronic pulmonary heart diseases]
• [Colocalization of 11beta-hydroxysteroid dehydrogenase type I and glucocorticoid receptor and its significance in rat hippocampus]
• [Effect of "yang wei kang liu" granula on expression of P53 and PCNA in mice bearing sarcoma 180]
• [Effects of ATP concentration and hypoxic exposure on RNA and protein synthesis activity in isolated mitochondria from rat brain]
• [Effects of Ulinastatin on the intestinal mucosal barrier of the mini-pigs after severe burn injury]
• [Expression of recombinant human Flt3 ligand in Escherichia coli and its purification and characterization]
• [Expression of transporter associated with antigen processing (TAP) in childhood acute leukemia and its clinical significance]
• [Influence of prostaglandin E2 on proliferation of melanocytes in full-thickness skin graft]
• [Investigation and evaluation on the harmfulness of partial vibration and the contact vibration time]
• [Okadaic acid induces the expression of glutamate transporter EAAT1 in the neurons of rat brain]
• [Pathology and pathophysiology of severe acute respiratory syndrome]
• [Protective effect of exogenous bcl-2 on spinal cord motoneurons following sciatic nerve axotomy in the rat]
• [Risk factors for malignant pleural mesothelioma in crocidolite contaminated area]
• [Selection of vestibular system function in Chinese astronauts]
• [Spatial autocorrelation analysis on schistosomiasis cases and Oncomelania snails in three provinces of the lower reach of Yangtze River]
• [Studies on crosslinkable coatings for biomedical application]
• [Study on the relationship between the opacity of lens and the levels of 2, 6-dinitro-4-amino-toluene (DNAT) in the urine of workers exposed to trinitrotoluene(TNT)]
• [The association between glucocorticoid receptor gene G1666T polymorphism and cerebral infarction in Chinese]
• [The effects of NO inhalation on cardice function in the burn patients with inhalation injury]
• [The expression of nestin in ischemia-injured brain of adult rat]
• [The neuromuscular transmission effects induced by pralidoxine chloride on rats with acute isocarbophos poisoning]