The application of post-market monitoring to novel foods.

The application of post-market monitoring to novel foods. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

The application of post-market monitoring to novel foods. Abstract Text:

P Hepburn,J Howlett,H Boeing,A Cockburn,A Constable,A Davi,N de Jong,B Moseley,R ,C Robertson,J M Wal,F Samuels,P Hepburn,J Howlett,H Boeing,A Cockburn,A Constable,A Davi,N de Jong,B Moseley,R Oberdörfer,C Robertson,J M Wal,F Samuels,

The role of post-market monitoring (PMM) in the safety assessment of novel foods is critically discussed in order to derive guidelines as to in which situations the application of PMM might be warranted. Available data sources on food consumption and health status, and the methodologies for generating such data are reviewed. The paper suggests improvements to make them more applicable for PMM purposes. It is concluded that any PMM programme must be a hypothesis-driven scientific exercise. PMM can have a role as a complement to, but not as a replacement for, a comprehensive pre-market safety assessment. Its use may be appropriate to confirm that product use is as predicted in the pre-market assessment; to provide reassurance that effects observed in the pre-market assessment occur with no greater frequency or intensity in the post-market phase than anticipated; and to investigate the significance of any adverse effects reported by consumers after market-launch. However PMM is insufficiently powerful to test the hypothesis that any effects seen in the pre-market assessment are absent in the post-market phase. Current methodologies place limitations on what PMM can achieve. PMM should only be used when triggered by or when the focus is on specific evidence-based questions.

The application of post-market monitoring to novel foods. Publishing Authors By Initials

P Hepburn,J Howlett,H Boeing,A Cockburn,A Constable,A Davi,N de Jong,B Moseley,R ,C Robertson,JM Wal,F Samuels,P Hepburn,J Howlett,H Boeing,A Cockburn,A Constable,A Davi,N de Jong,B Moseley,R Oberdörfer,C Robertson,JM Wal,F Samuels,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

The application of post-market monitoring to novel foods. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Food and chemical toxicology : an international jo

VOLUME: 46

Page Numbers: 9-33

Journal Abbreviation: Food Chem. Toxicol.

ISSN: 0278-6915

DAY: 14

MONTH: 09

YEAR: 2007

The application of post-market monitoring to novel foods. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8207483

The application of post-market monitoring to novel foods. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: The application of post-market monitoring to novel foods. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for The application of post-market monitoring to novel foods.

AFFILIATION: Unilever, Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Befordshire MK44 1LQ, United Kingdom.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Food Chem Toxicol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

The application of post-market monitoring to novel foods Related Publications

• Artificial regulation of ospC expression in Borrelia burgdorferi.
• California surveillance for pesticide-related illness and injury: coverage, bias, and limitations.
• Cancer chemotherapeutic response and intravenous hyperalimentaion.
• Characterization of Arabidopsis ABCG11/WBC11, an ATP binding cassette (ABC) transporter that is required for cuticular lipid secretion.
• Clinical trial of bleomycin (NSC-125066) in the treatment of metastatic renal carcinoma.
• Clozapine use in a forensic population in a New South Wales prison hospital.
• Combination vincristine (NSC-67574) and hydroxyurea (NSC-32065) for metastatic renal carcinoma.
• Early effects of testosterone propionate on the seminal vesicles of castrate rats.
• Farnesyl pyrophosphate is a novel transcriptional activator for a subset of nuclear hormone receptors.
• Genetics of cholesterol and lipoprotein metabolism.
• Gill Samuels.
• History of safe use as applied to the safety assessment of novel foods and foods derived from genetically modified organisms.
• Industrial accidents and peripheral vascular diseases.
• Influence of previous diet on metabolism during fasting.
• Intrathecal methotrexate (NSC-740) therapy for brain tumors in children.
• Meeting the health needs of rural America--the Kirksville mission.
• Mitochondrial AZT metabolism.
• Necrosis of intraocular tissues.
• Nuclear receptor coregulator (NRC): mapping of the dimerization domain, activation of p53 and STAT-2, and identification of the activation domain AD2 necessary for nuclear receptor signaling.
• PARTICIPATION OF THE OCULAR APPENDAGES IN SYMPATHETIC OPHTHALMIA AND ITS BEARING ON ENUCLEATION.
• Psychiatrists' ascertained treatment needs for mental disorders in a population-based sample.
• Role of PSF-TFE3 oncoprotein in the development of papillary renal cell carcinomas.
• SPECTROFLUORIMETRIC MEASUREMENT OF 1,3-DIAMINO-5-METHYLPHENAZINIUM CHLORIDE (NSC-33419) IN URINE.
• Selection against Pathogenic mtDNA Mutations in a Stem Cell Population Leads to the Loss of the 3243A-->G Mutation in Blood.
• Sleep, recovery, and performance: the new frontier in high-performance athletics.
• Temperature-induced regulation of RpoS by a small RNA in Borrelia burgdorferi.
• The application of post-market monitoring to novel foods.
• The effects of promazine on psychiatric symptoms.
• Thiopropazate hydrochloride (dartal) chemotherapy for emotional disorders; a clinical evaluation.
• Varieties of dual-process theory for probabilistic reasoning.