The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties.

The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties. Research Abstract Details 

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The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties. Abstract Text:

S Meuer,S Becker,U Hadding,D Bitter-Suermann,

Highly purified guinea pig C3a was obtained after specific cleavage of isolated C3 by the alternative pathway enzyme VF-B in a one step procedure. It turned out to be a low molecular weight peptide with basic character (M.W. 9500; isoelectric point above 9.4). C3a represents an antigenetic determinant of its own in the native C3 molecule, different from the B determinant. Guinea pig C3a resistant to 100 degrees C for 10 minutes. Its smooth muscle contracting activity can be destroyed by trypsin and carboxypeptidase B. These findings indicate that guinea pig C3a is quite similar to human C3a.

The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties. Publishing Authors By Initials

S Meuer,S Becker,U Hadding,D Bitter-Suermann,

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The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zeitschrift für Immunitätsforschung. Immunobiology

VOLUME: 154

Page Numbers: 135-46

Journal Abbreviation:

ISSN: 0340-904X

DAY: 12

MONTH: Mar

YEAR: 1978

The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties. Information

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LANGUAGE: eng

NlmUniqueID: 7608602

The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties. Keywords Mesh Terms:

KEYWORDS: Peptides

MESH TERMS: drug effects

Chemical & Substance for Abstract: The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties. Information

Substance Name: Carboxypeptidases

Registry Number: EC 3.4.-

Grant and Affiliation Information for The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenetic properties.

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Country: GERMANY, WEST

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MEDLINETA: Z Immunitatsforsch Immunobiol

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