Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp.

Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp. Research Abstract Details 

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Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp. Abstract Text:

Dong-Chan Oh,Wendy K Strangman,Christopher A Kauffman,Paul R Jensen,William Fenical,

[structure: see text] Two new cyclic peptides, thalassospiramides A and B (1 and 2), were isolated from a new member of the marine alpha-proteobacterium Thalassospira. The thalassospiramides, the structures of which were assigned by combined spectral and chemical methods, bear unusual gamma-amino acids and show immunosuppressive activity in an interleukin-5 production inhibition assay (IC50 = 5 muM for thalassospiramide B).

Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp. Publishing Authors By Initials

DC Oh,WK Strangman,CA Kauffman,PR Jensen,W Fenical,

For similar bacteria: gram-negative bacteria: gram-negative aerobic bacteria: gram-negative aerobic rods and cocci: rhodospirillaceae research abstracts see: bacteria: gram-negative bacteria: gram-negative aerobic bacteria: gram-negative aerobic rods and cocci: rhodospirillaceae research

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Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Organic letters

VOLUME: 9

Page Numbers: 1525-8

Journal Abbreviation:

ISSN: 1523-7060

DAY: 21

MONTH: 03

YEAR: 2007

Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100890393

Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp. Keywords Mesh Terms:

KEYWORDS: Rhodospirillaceae

MESH TERMS: metabolism

Chemical & Substance for Abstract: Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp. Information

Substance Name: thalassospiramide B

Registry Number: 0

Grant and Affiliation Information for Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp.

AFFILIATION: Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California-San Diego, La Jolla, California 92093, USA.

Country: United States

AGENCY: United States NCI

GRANT: CA44848

ACRONYM: CA

MEDLINETA: Org Lett

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